Endocrine-disruptor molecular responses, occurrence of intersex and gonado-histopathological changes in tilapia species from a tropical freshwater dam (Awba Dam) in Ibadan, Nigeria

Adeogun, Aina O.; Onibonoje, Kolawole; Ibor, Oju R.; Omiwole, Roseline A.; Chukwuka, Azubuike V.; Ugwumba, Alex O.; Ugwumba, A. A. A.; Arukwe, Augustine

doi:10.1016/j.aquatox.2016.02.002

Cited by 42 publications

(15 citation statements)

References 61 publications

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“…Histological alterations of gonads of fish resulting from environmental pollutants have been researched to be an effective biomarker tool in environmental monitoring [28]. Similar findings to results from this study on the effects of pollutants on fish have been reported [29,30]. The information provided in this study reveals that fish histopathology could be used as biomarkers to provide details on the effects of hydrocarbons on fish health.…”

Section: Fig 6 -Histology Of Liver Of the African Catfish (Clarias Gsupporting

confidence: 86%

Histopathological Biomarkers of Exposure to Monocyclic Aromatic Hydrocarbons in Clarias Ggariepinus (African Catfish)

Doherty

Adeola

Aneyo

et al. 2019

JST

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Section: Fig 6 -Histology Of Liver Of the African Catfish (Clarias Gsupporting

confidence: 86%

Histopathological Biomarkers of Exposure to Monocyclic Aromatic Hydrocarbons in Clarias Ggariepinus (African Catfish)

Doherty

Adeola

Aneyo

et al. 2019

JST

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“…Male vtg expression increased directly downstream of the treatment plants in some years. Increases in vtg expression have been associated with the presence of estrogenic compounds [ 68 – 70 ] and are frequently found downstream of MWWTPs [ 71 – 73 ]. Male gonad sex steroid production and gonad development were found to be decreased and delayed, respectively.…”

Section: Discussionmentioning

confidence: 99%

An Assessment of the Spatial and Temporal Variability of Biological Responses to Municipal Wastewater Effluent in Rainbow Darter (Etheostoma caeruleum) Collected along an Urban Gradient

et al. 2016

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Municipal wastewater effluent (MWWE) and its constituents, such as chemicals of emerging concern, pose a potential threat to the sustainability of fish populations by disrupting key endocrine functions in aquatic organisms. While studies have demonstrated changes in biological markers of exposure of aquatic organisms to groups of chemicals of emerging concern, the variability of these markers over time has not been sufficiently described in wild fish species. The aim of this study was to assess the spatial and temporal variability of biological markers in response to MWWE exposure and to test the consistency of these responses between seasons and among years. Rainbow darter (Etheostoma caeruleum) were collected in spring and fall seasons over a 5-year period in the Grand River, Ontario, Canada. In addition to surface water chemistry (nutrients and selected pharmaceuticals), measures were taken across levels of biological organization in rainbow darter. The measurements of hormone production, gonad development, and intersex severity were temporally consistent and suggested impaired reproduction in male fish collected downstream of MWWE outfalls. In contrast, ovarian development and hormone production in females appeared to be influenced more by urbanization than MWWE. Measures of gene expression and somatic indices were highly variable between sites and years, respectively, and were inconclusive in terms of the impacts of MWWE overall. Robust biomonitoring programs must consider these factors in both the design and interpretation of results, especially when spatial and temporal sampling of biological endpoints is limited. Assessing the effects of contaminants and other stressors on fish in watersheds would be greatly enhanced by an approach that considers natural variability in the endpoints being measured.

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“…Perhaps the idea of investigating the possible risk associated with exposure to these contaminants is still burgeoning in these regions or lack of highly sensitive instruments to determine the levels of these contaminants may be the contributing factors to the scarcity of data. Although scientific evaluation of the risk associated with these contaminants in the natural environment have been criticized by some scholars to be a waste of time due to their extremely low levels [71] visible adverse effects resulting in hormonal and other sexual disorders have been observed and reported in some vertebrate and non-vertebrate species which were scientifically traced to these contaminants [24][25][26]. Even though direct link with human health is yet to be established, it may be possible that the human health effects is cumulative and may manifest over time in areas with large influx and usage of these chemicals with little or no regulation or remediation strategies.…”

Section: Analysis and Environmental Concentrationsmentioning

confidence: 99%

“…Adverse effects of some of these compounds have been observed in aquatic organisms. Several reproductive anomalies have been reported in vertebrate and non-vertebrate aquatic species due to exposure to endocrine disrupting compounds (EDC's) [24][25][26]. Also, EDC's have been recently matched with the ability to interfere with thyroid function or lipid signalling and consequently produce metabolic disruption or incidence of metabolic diseases such as obesity and diabetes, through the activation of peroxisome proliferator activated receptors (PPARs) [27][28][29].…”

Section: Introductionmentioning

confidence: 99%

Preliminary Review of Sources, Fate, Analytical Challenges and Regulatory Status of Emerging Organic Contaminants in Aquatic Environments in Selected African Countries

2019

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Emerging contaminants (ECs) have received great attention in developed countries and as such some of them have received priority screening and regulatory guidelines proposed. However, due to the requirements of highly sensitive and sophisticated analytical equipment, research on this subject in developing countries in Africa are very scarce. We carried out a review of published data from southern and western African region in order to: (1) highlight the environmental concentrations of ECs in West and Southern Africa and bring to light the analytical challenges in order to elicit discussions on solutions, (2) analyse the state of science regarding ECs in African environment and summarise available data for comparative analysis. Generally, the study reveals that in spite of the scanty data reported, levels of ECs are in the upper range of global concentrations. Monitoring data are increasing yearly, although at a very slow rate. Environmentally relevant levels reported are high enough to cause potential risks. Priority monitoring of phenolic endocrine disrupting compounds, phthalate esters, triclosan, triclocarban and some pharmaceutical active compounds (PhACs) like ibuprofen are recommended due to high frequency of detection. Understudied compounds should be prioritized for toxicity studies, monitoring and potential risk evaluation in order to increase knowledge on their sources and fate for proper management.

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Endocrine-disruptor molecular responses, occurrence of intersex and gonado-histopathological changes in tilapia species from a tropical freshwater dam (Awba Dam) in Ibadan, Nigeria

Cited by 42 publications

References 61 publications

Histopathological Biomarkers of Exposure to Monocyclic Aromatic Hydrocarbons in Clarias Ggariepinus (African Catfish)

Histopathological Biomarkers of Exposure to Monocyclic Aromatic Hydrocarbons in Clarias Ggariepinus (African Catfish)

An Assessment of the Spatial and Temporal Variability of Biological Responses to Municipal Wastewater Effluent in Rainbow Darter (Etheostoma caeruleum) Collected along an Urban Gradient

Preliminary Review of Sources, Fate, Analytical Challenges and Regulatory Status of Emerging Organic Contaminants in Aquatic Environments in Selected African Countries

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