2024
DOI: 10.1007/s40618-024-02371-w
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Endocrine disruptors, aryl hydrocarbon receptor and cortisol secretion

F. Pecori Giraldi,
F. Ferraù,
M. Ragonese
et al.

Abstract: Purpose Endocrine disruptors exert a plethora of effects in endocrine tissues, from altered function to carcinogenesis. Given its lipophilic nature, the adrenal cortex represents an ideal target for endocrine disruptors and thus, possibly, xenobiotic-induced adrenocortical dysfunction. However, there is no clear understanding of the effect of endocrine disruptors on adrenal steroidogenesis, in particular as regards the aryl hydrocarbon receptor (AHR) pathway, one of the key mediators. … Show more

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