Endodontic Infections in Incompletely Developed Teeth

Huang, George T.‐J.; Ricucci, Domenico; Lin, Louis M.

doi:10.1002/9781119080343.ch14

Cited by 4 publications

(3 citation statements)

References 183 publications

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“…Direct extension from an odontogenic infection is implicated for Moyoro 165 by the clear evidence of alveolar involvement and tooth loss, and by the localized nature of the lesion. Because developing and erupting teeth are particularly susceptible to infection (Huang, 2009), the Moyoro child's young age is compatible with OM development secondary to an infected tooth germ (e.g., tooth 34 and/or tooth 35). However, a periapical infection from caries or direct trauma, or a periodontal infection associated with a recently erupted tooth (e.g., tooth 74 and/or 75), are also possible etiological mechanisms (Oulis et al, 2000;Belli et al, 2002;Chang et al, 2015;Fukuda et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Pediatric mandibular osteomyelitis: a probable case from Okhotsk period (5th–13th century AD) northern Japan

Lieverse

Kubo

Bourgeois

et al. 2022

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Section: Discussionmentioning

confidence: 99%

Pediatric mandibular osteomyelitis: a probable case from Okhotsk period (5th–13th century AD) northern Japan

Lieverse

Kubo

Bourgeois

et al. 2022

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“…Thus, local immunological and microbiological factors are important in the disease's etiology and pathogenesis (Baltensperger and Eyrich, 2009;Slootweg, 2010). Immature teeth are especially susceptible to infection because of incomplete root formation with open apices and large canal sizes (Huang, 2009). Further, because common nonpathogenic oral microorganisms have the potential to cause infection (Willet et al, 1991), osteomyelitis is possible even in the absence of carious or periodontal lesions, as is argued for this case.…”

mentioning

confidence: 85%

A unique case of mandibular osteomyelitis arising from tooth germ infection in a 7,000-year-old infant from Siberia

Waters‐Rist¹

2018

DAJ

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Excavations from a 7,000-year-old mortuary site in the Lake Baikal region of Siberia, Russian Federation, revealed an infant with osteomyelitis of the mandible. The lesion exhibits deformation of the anterior mandibular base, an extra-oral cloaca, and new periosteal bone layers on the corpus. Entry of oral microorganisms was likely via the deciduous left canine, with infection then concentrated around the forming permanent canine tooth germ. This infection route is not widely documented in paleopathology and the pathogenicity of oral microorganisms is discussed. This unique case is one of the oldest examples of infant osteomyelitis of the jaws, adding to our understanding of the antiquity and development of infectious diseases in humankind.

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“…51 They are induced by overlapping dental lamina during odontogenesis originating from ecto-mesenchymal tissue. 56,57 These stem cells are responsible for the development of the tooth structure and the pulp tissue. SCAPs form a concentrated area of cells between the pulp complex and the apical papilla.…”

Section: Stem Cells From the Dental Apical Papilla Scapsmentioning

confidence: 99%

Untitled

2019

JSRT

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Since the discovery of dental mesenchymal stem cells (DMSCs), there has been an extensive amount of research into their proliferating capabilities. DMSCs are extracted from exfoliated deciduous teeth, wisdom teeth, postnatal teeth, the periodontium, and alveolar bone. DMSCs have been shown to heal periodontal diseases and improve bone augmentation. DMSCs are accessible to all dentists. These qualities make DMSCs a promising source for tooth regeneration. There are numerous studies discussed in this article that offer encouraging evidence for the development of dental tissue regeneration. Eight different DMSC types are classified in this review: Dental Pulp Stem Cells (DPSCs), Stem cells from Human Exfoliated Deciduous teeth (SHEDs), Periodontal Ligament Stem Cells (PDLSCs), Dental Follicle Stem Cells (DFSCs), Stem Cells from the Dental Apical Papilla (SCAPs) Alveolar Bone-Derived MSCs (ABMSCs), Tooth Germ Progenitor cells (TGPCs), and Gingival MSCs (GMSCs), respectively. The discovery of DMSCs for regenerative medicine has attracted a profound amount of research. Additional clinical experimentation is required to test their medical and dental practicalities. This article is a review of the characterization, isolation, and the literature of previous studies on dental stem cell capabilities in regenerative medicine and their clinical applications for future dental practitioners.

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Endodontic Infections in Incompletely Developed Teeth

Cited by 4 publications

References 183 publications

Pediatric mandibular osteomyelitis: a probable case from Okhotsk period (5th–13th century AD) northern Japan

Pediatric mandibular osteomyelitis: a probable case from Okhotsk period (5th–13th century AD) northern Japan

A unique case of mandibular osteomyelitis arising from tooth germ infection in a 7,000-year-old infant from Siberia

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