Endodontic management of open apex using MTA and platelet - rich fibrin membrane barrier: A newer matrix concept

Khetarpal, Ambica; Chaudhry, Sarika; Talwar, Sangeeta; Verma, Mahesh

doi:10.4317/jced.51178

Cited by 23 publications

(18 citation statements)

References 14 publications

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“…Platelet-rich Fibrin (PRF) is a matrix of platelet and leukocyte cytokines embedded in autologous fibrin and used as an apical membrane [61] (Fig. 1).…”

Section: Mta and Platelet Rich Fibrin (Prf) Membranementioning

confidence: 99%

“…It facilitates neo-angiogenesis, vascularization and graft survival. It also accelerates the healing of wound edges preventing the extrusion of the material into the periodontal tissues, allowing a favourable response by periodontal tissues [61].…”

Section: Causes Crown Discolourationmentioning

confidence: 99%

“…It creates healing via platelet cytokines (PDGF, TGF-IGF-1), and the presence of leukocytes, cytokines in the fibrin network self-regulates inflammation, and infection within the grafted material [61]. Different materials used in open apex treatment, their applications, advantages and disadvantages are listed in Table 3.…”

Section: Mechanism Of Actionmentioning

confidence: 99%

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Endodontic treatment of immature tooth – a challenge

Gupta¹,

Sodhi²,

Brar³

et al. 2020

J Pre Clin Clin Res.

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Root apex is an area of primary importance for an endodontist. When a tooth erupts in the oral cavity the apical foramen undergoes anatomical changes with age. Root development is completed and the root apex is closed three years after eruption of the tooth. Endodontic practice is influenced to a great extent by different stages of root development and the type of tissue present within the roots. Open apices pose a challenging problem for the success of root canal treatment because they favour the extravasation of the irrigating solution and/or sealer into periradicular tissues, thus jeopardizing apical healing. Regenerative endodontics (revascularization/pulpal regeneration) is a straightforward approach accomplished with currently available instruments and materials. A literature review suggests that Mineral Tri oxide Aggregate (MTA) is the most favourable and recommendable material for single-visit apexification, even in cases when regenerative endodontics cannot be performed. A plus point of MTA is its biocompatibility and hermetic apical seal with no micro-leakage. It should be considered as an effective alternate for treating immature teeth with necrotic pulps. Treatment of a tooth with open apex poses multiple challenges. However, it is not easy to decide which material should be used: Calcium hydroxide, Mineral Tri oxide Aggregate, Biodentine, Platlet Rich Fibrin (PRF), or White Portland Cement (WPC). The choice of treatment regimen depends on several factors, e.g. individual cases, experience of the operator, familiarity with handling various materials, and patient's availability for follow-up appointments. This review highlights various challenges in the treatment of open apex, with emphasis on MTA compared with other materials.

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“…Platelet-rich Fibrin (PRF) is a matrix of platelet and leukocyte cytokines embedded in autologous fibrin and used as an apical membrane [61] (Fig. 1).…”

Section: Mta and Platelet Rich Fibrin (Prf) Membranementioning

confidence: 99%

Section: Causes Crown Discolourationmentioning

confidence: 99%

See 1 more Smart Citation

Endodontic treatment of immature tooth – a challenge

Gupta¹,

Sodhi²,

Brar³

et al. 2020

J Pre Clin Clin Res.

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show abstract

“…To form the apical matrix barrier, a platelet-rich fibrin (PRF) membrane was prepared as follows: 12 mL of whole blood was intravenously drawn from the patient' s right antecubital vein and centrifuged at 3000 rpm for 10 min. This formed three layers in the tube : a layer of red blood cells at the bottom, an acellular plasma at the top, and a PRF clot in the middle8) . The PRF clot was separated and pressed between two gauzes to create a Preoperative panoramic radiograph of the 13-year-old female patient.…”

mentioning

confidence: 99%

Autotransplantation of Ectopically Impacted Teeth : Two Case Reports

Lim¹,

Kim²,

Choi³

et al. 2017

THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY

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Numerous therapeutic approaches are available for impacted teeth, including orthodontic retraction, implantation, and autogenous tooth transplantation. Autotransplantation is a promising method, especially for juvenile patients, as it enables preservation of the function of the periodontal tissues, as well as continued alveolar bone growth. This report describes autotransplantation in two cases in which the tooth was fully-ectopically impacted. With case 1, an ectopically impacted premolar was extracted and transplanted in an upright position, and regenerative endodontic treatment was performed using a platelet-rich fibrin clot and mineral trioxide aggregate (MTA). With case 2, a calcifying odontogenic cyst with an impacted left mandibular second molar was treated by enucleation. The tooth was transplanted into the proper position 3 months after enucleation, and endodontic treatment was performed using MTA. In both cases, autotransplantation appeared to provide a simple and rapid treatment option for patients with ectopically impacted teeth. These cases demonstrate that autotransplantation of ectopically impacted teeth is a viable treatment option rather than implant placement or prosthesis, especially in juvenile patients.

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“…Shivashankar et al 24 , Khetarpal et al 25 and Rudagi & Rudagi and apical bone formation. Shivashankar et al 24 concluded that revitalization of necrotic infected immature tooth is possible under conditions of total canal disinfection and PRF is an ideal biomaterial for pulp-dentin complex regeneration. Use of MTA and PRF for the repair of the perforation defect and Grade II furcation has resulted in long term results with regeneration of the lost periodontium in furcation area.…”

mentioning

confidence: 99%

Platelet-Rich Fibrin: Role in Periodontal and Pulpal Regeneration

Mohamed¹

2017

jmscr

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Endodontic management of open apex using MTA and platelet - rich fibrin membrane barrier: A newer matrix concept

Cited by 23 publications

References 14 publications

Endodontic treatment of immature tooth – a challenge

Endodontic treatment of immature tooth – a challenge

Autotransplantation of Ectopically Impacted Teeth : Two Case Reports

Platelet-Rich Fibrin: Role in Periodontal and Pulpal Regeneration

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