Endogenous Toll-like Receptor 4 Deletion Significantly Improves Wound Healing in a Murine Model of Diabetic-ischaemic Ulceration

Abstract

cells (transplantation of ApoeÀ/À aortas into CCL5À/À ApoeÀ/À mice). Conclusion:These results indicate that CCL5 expressed in cells of the vascular wall plays an important role in the recruitment of monocytes / macrophages to transplanted vessels and may thereby contribute to the development of atherosclerotic lesions after aortic transplantation.