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Unlike Schneiderian papilloma, a widespread benign epithelial neoplasm arising in the sinonasal tract mucosa of the nasal cavity, paranasal sinus, trachea, and larynx, middle-ear Schneiderian papilloma is extremely rare. We report a case of recurrent Schneiderian papilloma spreading to the bilateral middle ear and right paranasal sinus, and eventually causing cerebellar complications. A-52-year old woman seen for episodes of inarticulateness was first, found to have middle right ear and right ethmoid papilloma, that occurred thereafter is the middle left ear. This bilateral middle-ear papilloma is, to our knowledge, the only case reported thus far, and fell into a low-risk malignant formation group based on HPV-DNA testing. Given previous cases, we concluded that ours warranted meticulous follow-up because recurrence and malignancy are more common in multiple-site middle-ear papilloma as in our case rather than papilloma of the middle ear alone.
Unlike Schneiderian papilloma, a widespread benign epithelial neoplasm arising in the sinonasal tract mucosa of the nasal cavity, paranasal sinus, trachea, and larynx, middle-ear Schneiderian papilloma is extremely rare. We report a case of recurrent Schneiderian papilloma spreading to the bilateral middle ear and right paranasal sinus, and eventually causing cerebellar complications. A-52-year old woman seen for episodes of inarticulateness was first, found to have middle right ear and right ethmoid papilloma, that occurred thereafter is the middle left ear. This bilateral middle-ear papilloma is, to our knowledge, the only case reported thus far, and fell into a low-risk malignant formation group based on HPV-DNA testing. Given previous cases, we concluded that ours warranted meticulous follow-up because recurrence and malignancy are more common in multiple-site middle-ear papilloma as in our case rather than papilloma of the middle ear alone.
Endolympathic sac tumor is a rare temporal bone neoplasm, and is considered to be a low-grade adenocarcinoma. Despite its slow growth and low incidence of association with distant metastasis, this tumor often shows aggressive local bone destruction. Herein, we report a rare case. A 52-year-old man with Down syndrome presented with a 6-month history of hemifacial palsy. The initial examination revealed left-sided complete facial nerve palsy. Analysis of the auditory brain stem response indicated deafness on the affected side. The patient had no vertigo or nystagmus. Computed tomography revealed a well-defined osteolytic soft tissue lesion in the left petrous bone. The lesion was seen as a high intensity on both T1-and T2-weighted magnetic resonance images, and showed heterogeneous gadolinium enhancement. The labyrinth was destroyed, and the internal acoustic meatus was indistinguishable. Under a tentative diagnosis of cholesterol glanuloma, transmastoid biopsy was performed. The histopathological diagnosis was endolymphatic sac tumor. The patient eventually underwent removal of the tumor via a trans-middle cranial fossa approach following preoperative arterial embolization. His postoperative clinical course was uneventful, and he was discharged 19 days after the surgery. Although the facial nerve palsy or hearing loss did not recover, no evidence of tumor recurrence has been seen over a postoperative follow-up period of 32 months. A bibliographic review of the clinical/ histopathological characteristics, diagnosis and treatement of endolymphatic sac tumor is presented.
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