Endometrial adenocarcinoma arising in adenomyosis: case report and review of literature

Endometrial Cancer Arising in Adenomyosis (EC-AIA): A Systematic Review

“…For the "unbiased study endpoints" domain, the risk of bias was low in 14 studies [13,14,17,18,20,24,[29][30][31][32][33]37,39,40,42], unclear in 11 studies [15,16,19,22,23,[26][27][28]34,35], and high in six studies [12,21,25,36,38,41]; in particular, in the studies at high risk of bias, Colman and Rosenthal's criteria were only partially fulfilled.…”

“…All included studies were case reports [36][37][38][39][40][41], except for four case series [12,34,35,42] (Table 1).…”

“…For the "patient selection" domain (when applicable), two studies were considered at low risk of bias [12,42], while two studies were judged as having unclear risk of bias [34,35]. For the "study endpoints" domain, the risk of bias was considered low in 15 studies [12][13][14]17,18,20,21,24,[29][30][31][32][33]37,41,42], while it was unclear in 16 studies [15,16,19,22,23,[25][26][27][28][34][35][36][38][39][40].…”

“…For the "patient selection" domain (when applicable), two studies were consid low risk of bias [12,42], while two studies were judged as having unclear risk of bias For the "study endpoints" domain, the risk of bias was considered low in For the "follow-up" domain, four studies were at low risk of bias [17,18,29,42], 15 were at unclear risk of bias [15,16,22,23,[25][26][27][28][34][35][36][38][39][40], and 12 studies were at high risk of bias [12][13][14][19][20][21]24,[30][31][32][33]37,41]; in particular, in studies at high risk of bias, the follow-up duration was less than 24 months.…”