Endometrial carcinoma arising in one horn of a didelphys uterus

Vanichtantikul, Asama; Huang, Kuan-Gen; Hsu, Chin-Chieh

doi:10.1016/j.tjog.2019.11.028

Cited by 6 publications

(11 citation statements)

References 5 publications

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“…We found only 18 cases of uterine didelphys complicated by malignant tumors, including 15 cases of EC, 2 cases of carcinosarcoma, and 1 case of sarcoma. [9,[11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] The incidence of bilateral uterine involvement was even lower, with only 3 cases reported in the literature, including 1 case of sarcoma. In our patient, diagnostic curettage revealed involvement of both the uterine cavity and cervix; therefore, modified radical hysterectomy was chosen.…”

Section: Discussionmentioning

confidence: 99%

Uterus didelphys complicated with endometrial carcinoma

Chen

Zhang

et al. 2022

Medicine

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Rationale:The incidence of uterine malformations is low (4%–7%). Currently, the National Comprehensive Cancer Network clinical practice guidelines in oncology recommend minimally invasive surgery for early endometrial cancer. Minimally invasive surgery for the treatment of uterine didelphys with endometrial cancer is rare due to the large size of the uterus. To date, only 2 such patients have been reported to have undergone laparoscopy. Whether such patients can be treated with minimally invasive surgery needs to be further explored.Patient concerns:A 40-year-old woman with uterine didelphys was hospitalized for menorrhagia in the past 2 months.Diagnosis:Endometrial adenocarcinoma was found in both the uterus and cervix using fractional dilation and curettage.Interventions:The patient underwent laparoscopic surgery. Postoperative adjuvant radiotherapy and chemotherapy were administered.Outcomes:There was no sign of recurrence during routine follow-up.Lessons:The use of a uterine manipulator to lift either side of the uterus could help to expose the narrow ipsilateral para-uterine field. It is difficult to remove the uterus entirely through the vagina, making it necessary to select appropriate cases wherein screening is performed to check if the vagina is loose, and the uterus is of appropriate size. Minimally invasive surgery may be feasible for suitable patients.

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Section: Discussionmentioning

confidence: 99%

Uterus didelphys complicated with endometrial carcinoma

Chen

Zhang

et al. 2022

Medicine

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“…We reviewed published articles about uterus didelphys combining endometrial cancer in PubMed from 1990 to 2020 [ 8 – 22 ]. There are 15 cases included, the age of onset ranged from 33 to 75 years old.…”

Section: Discussionmentioning

confidence: 99%

Fertility preservation in patients with uterus didelphys and endometrial carcinoma: a case report

Shang

Wen

et al. 2021

BMC Women's Health

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Background Endometrial cancer combining uterus didelphys is quite rare clinically which partially explains that there is no discussion about young patients’ fertility preservation and follow up of tumor outcome. Case presentation In this article, we report a case of unilateral endometrial carcinoma found in a young patient with uterus didelphys who was treated with high-efficiency progesterone due to unfinished child-bearing. During the follow-up, the affected uterine endometrium was not reversed by progesterone. So, the patient underwent the abdominal surgery with the left uterus and left fallopian tube resection. We performed three consecutive immunohistochemical studies of the contralateral uterine endometrium to verify the safety of preserving the contralateral uterus and its appendages which preserved her fertility. Conclusions Endometrial cancer occurring in patients with uterus didelphys is quite rare in child-bearing age. In this case report, we preserved the patient’s contralateral uterus based on patient’s strong needs and negative IHC analysis of the preserved side uterine endometrium. However, the tumor and fertility outcome require more follow-up.

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“…However, endometrial carcinoma in uterine didelphys has been reported in only a few case reports and case series ( Gao et al, 2017 , Molpus et al, 2004 ). When endometrial carcinoma is present in a didelphic uterus, it usually occurs in only one of the uterine horns ( Vanichtantikul et al, 2020 , Molpus et al, 2004 ). For this reason, when performing preoperative biopsies to rule out neoplasia, both uterine horns should be sampled because a negative finding in one does not exclude the presence of a neoplastic process in the other.…”

Section: Discussionmentioning

confidence: 99%

“…Most patients with endometrial carcinoma with uterine didelphys receive surgical management with total abdominal hysterectomy, bilateral salpingo-oophorectomy and peritoneal washings ( Vanichtantikul et al, 2020 ). Our report is the first to document surgical management with sentinel lymph node mapping in a patient with endometrial carcinoma and uterine didelphys, despite the anatomic anomaly.…”

Section: Discussionmentioning

confidence: 99%

“…Anatomical uterine anomalies are the most common type of congenital malformation in the female genital tract ( Gao et al, 2017 ). Although endometrial carcinoma is relatively common, the presence of endometrial carcinoma in patients with anatomical uterine anomalies has been documented only rarely in case reports and case series ( Gao et al, 2017 , Vanichtantikul et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

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Case report: Sentinel lymph node mapping of endometrial carcinoma occurring in uterine didelphys

Sassine

Moufarrij

Hodgson

et al. 2021

Gynecologic Oncology Reports

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Highlights In a bleeding postmenopausal woman with didelphys uterus, endometrial biopsy should be taken from both uterine cavities. Sentinel lymph node mapping has not been previously described in the setting of endometrial cancer and uterine didelphys. Routine sentinel lymph node mapping was successfully performed in a patient with endometrial cancer and uterine didelphys.

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Endometrial carcinoma arising in one horn of a didelphys uterus

Cited by 6 publications

References 5 publications

Uterus didelphys complicated with endometrial carcinoma

Uterus didelphys complicated with endometrial carcinoma

Fertility preservation in patients with uterus didelphys and endometrial carcinoma: a case report

Case report: Sentinel lymph node mapping of endometrial carcinoma occurring in uterine didelphys

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