Endometrial tuberculosis in the Nigerian middle belt: an eight-year review

Abstract

Endometrial tuberculosis (TB) is a known cause of infertility in women which, because of the global increase in the spread of TB, should always be considered when investigating the cause of infertility. We undertook this review in order to determine its incidence among infertile women in the Nigerian middle belt. This is a retrospective study of all histopathological slides of infertile women seen at the University of Ilorin Teaching Hospital, Ilorin, Nigeria, between 1997 and 2004 who were evaluated for infertility by endometrial biopsy. The slides were reviewed and, where necessary, new sections were cut from tissue blocks and stained with haematoxylin and eosin. Ziehl-Neelsen stain used to demonstrate acid-fast bacilli. Clinical reports were extracted from histopathological request form. A total of 661 patients were included in the study. Primary infertility constituted 30%, secondary 69% and unspecified cases 1%. TB endometritis was seen in 0.45%. Endometrial TB is not a frequent cause of infertility in our set-up. However, with the worldwide resurgence of TB, its possible presence should always be taken into consideration.

Female genital tuberculosis: a clinicopathological report of 13 cases

“…Sometimes patients with FGTB present with a misleading clinical and radiological symptoms such as ascites or abdominal distension, leading to suspicion of malignant tumours especially in older patients [6, 7]. Also, FGTB is sometimes an incidental finding during investigations of women with infertility [4]. The upper genital tract (fallopian tubes and the endometrium) is mostly affected in FGTB [2, 5].…”

“…Genital tuberculosis (GTB) accounts for 15–20% of extrapulmonary TB (EPTB) [3]. The incidence of female genital tuberculosis (FGTB) is higher in developing countries; the disease usually affects the fallopian tubes and endometrium leading to infertility [4, 5]. The clinical presentation is usually indolent but may be particularly misleading as it can mimic other diseases especially malignant tumours leading to inappropriate clinical management [6, 7].…”

Gynecologic Infections

“…164 A few cases of non-neoplastic, lymphoma-like lesions of the cervix have been described. [186][187][188][189][190] An incidental case of uterine coccidioidomycosis was diagnosed at the time of hysterectomy for squamous carcinoma of the cervix. 166 Evidence of pemphigus can be found on cervical cytology.…”

Investigation of Toll-Like Receptor-2 (2258G/A) and Interferon Gamma (+874T/A) Gene Polymorphisms among Infertile Women with Female Genital Tuberculosis

“…Female genital tuberculosis (FGTB) is usually an asymptomatic disease diagnosed during investigations for infertility [ 1 – 3 ]. Genital tuberculosis (GTB) represents 15–20% of extra pulmonary tuberculosis (EPTB) [ 4 ].…”