“…Differential diagnosis may occur with umbilical hernia, primary umbilical cancer (squamous or basal cell carcinoma, melanoma, sarcoma, adenocarcinoma) or benign umbilical tumor (pyogenic granuloma, epidermal cyst, nevus melanocytic, histiocytofibroma) [12,13]. In gastric cancers, the presence of Sister Mary Joseph's nodule is a sign of poor prognosis, palliative chemotherapy is therefore proposed to the patient or a therapeutic abstention.…”