2001
DOI: 10.1006/gyno.2001.6382
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Endometriosis-Associated Ovarian Carcinoma (EAOC): An Entity Distinct from Other Ovarian Carcinomas as Suggested by a Nested Case-Control Study

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Cited by 141 publications
(61 citation statements)
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“…In addition, women with endometriosis often present with physical manifestations, such as pain and infertility, for which the diagnostic work up involves the same procedures used in the diagnosis of ovarian cancer. Thus, ovarian cancers among women with endometriosis tend to be diagnosed at an earlier stage and at a younger age [21,22]. It is possible that endometriosis could explain some of our findings, particularly why endometrioid and clear-cell carcinomas were diagnosed earlier than serous carcinomas.…”
Section: Discussionmentioning
confidence: 56%
“…In addition, women with endometriosis often present with physical manifestations, such as pain and infertility, for which the diagnostic work up involves the same procedures used in the diagnosis of ovarian cancer. Thus, ovarian cancers among women with endometriosis tend to be diagnosed at an earlier stage and at a younger age [21,22]. It is possible that endometriosis could explain some of our findings, particularly why endometrioid and clear-cell carcinomas were diagnosed earlier than serous carcinomas.…”
Section: Discussionmentioning
confidence: 56%
“…5,6 Due to these unique characteristics, ovarian cancers derived from the malignant transformation of endometriosis have been specifi cally referred to as endometriosis-associated ovarian cancer (EAOC). 7,8 Endometriosis as a neoplasm Endometriosis is currently classifi ed as a tumor-like lesion under both the WHO and Japanese ovarian tumor classification schemes. 9,10 However, a number of recent studies suggest that endometriosis is actually a clonal lesion.…”
Section: Masaki Mandai · Ken Yamaguchi · Noriomi Matsumura Tsukasa Bamentioning
confidence: 99%
“…Einige Autoren fanden bei EAOC eine günstigere Prognose [progressionsfreies ("progession-free survival", PFS) und Gesamtüberleben ("overall survival", OS] -und sprachen ihnen insgesamt den Status einer eigenen Entität zu [4,11,27,34], was von anderen hinsichtlich des Gesamtüberlebens nicht bestätigt werden konnte [9,23], wenn eine Adjustierung bezüglich Alter, Stadium, Differenzierungsgrad und Therapie (komplette Resektion ja/nein) im Vergleich mit anderen histologischen Typen ("high-grade"-serös) des Ovarialkarzinoms erfolgt. Wahrscheinlich erscheint die Prognose günstiger, weil mehr FIGO-Stadien I und II vorliegen und oft eine tumorfreie Resektion möglich ist -und vielleicht nicht per se wegen der Assoziation mit Endometriose [9,10,19,34].…”
Section: Bisherige Klinische Bedeutungunclassified
“…Endometriosis · Malignant tumors · Mutation · Endometrioma · Ovarian cancer vor allem für die extragonadalen EAM der Rektumwand, des Septum rectovaginale, der Parametrien oder Paraproktien gelten, wenn es sich -wie meistens -um ein rein pelvines Geschehen handelt [11,14,42]. Da diese Fälle Raritäten sind, gibt es keine allgemeingültigen Empfehlungen.…”
Section: Introductionunclassified