Endometriosis in Italy: From cost estimates to new medical treatment

Luisi, Stefano; Lazzeri, Lucia; Ciani, Valentina

doi:10.1080/09513590903159664

Cited by 8 publications

(13 citation statements)

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“…In Italy, for instance, it has been calculated that patients meet an average of about five physicians before diagnosis, and that requires an average of 9 years [9].…”

Section: Discussionmentioning

confidence: 99%

Unusually rapid growth of bilateral endometriomas and acute bilateral hydronephrosis

Gambadauro

Olovsson

Persson

2011

Gynecological Endocrinology

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Ultrasonography can detect ovarian endometriomas, but negative findings cannot exclude other localizations of endometriosis, especially in symptomatic patients. We describe a case of sudden development of large bilateral endometriomas after a series of negative ultrasound scans, causing bilateral hydronephrosis. Our patient is a 32-year-old nulligravida with long-lasting dysmenorrhea, urinary symptoms, and familiarity for endometriosis, who had voluntarily discontinued oral contraceptives. Various pelvic scans had not shown pathological findings. Five months following the last negative scan, she presented with pain and increase of abdominal girth. Ultrasonography and computed tomography showed large ovarian cysts (16 cm right - 10 cm left) and hydronephrosis bilaterally. She underwent conservative surgery followed by GnRH analogs. At a 6-months follow-up, she was symptom-free and ultrasonography showed no recurrence. Endometriosis has still an unknown mechanism of proliferation and its clinical behavior or progression is highly unpredictable. Severe uropathy is commonly related to direct ureteral involvement, but can also depend on an ab-extrinseco compression by large, rapidly growing endometriomas. Women at risk of endometriosis, who are not receiving empirical medical treatment, should be adequately and regularly assessed via pelvic ultrasonography and/or submitted to diagnostic laparoscopy in order to prevent serious consequences such as silent renal loss.

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“…In Italy, for instance, it has been calculated that patients meet an average of about five physicians before diagnosis, and that requires an average of 9 years [9].…”

Section: Discussionmentioning

confidence: 99%

Unusually rapid growth of bilateral endometriomas and acute bilateral hydronephrosis

Gambadauro

Olovsson

Persson

2011

Gynecological Endocrinology

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show abstract

“…italienische Frauen an Endometriose erkrankt sind (Luisi et al 2009). € pro Jahr geschätzt unter der Annahme, dass 3 Mio.…”

Section: Studien Zur Ermittlung Derunclassified

Leitsymptom chronischer Unterbauchschmerz der Frau

Sillem¹,

Siedentopf²,

Mechsner³

2015

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“…In the United States, endometriosis accounts for one third of hospital admissions for gynecological causes, 8 while one study conducted in Italy showed that the annual cost of inpatient treatment is about 54 million euros. 9 Broadening the spectrum of the 'endometriosis disease' to the 'endometriosis syndrome', several studies demonstrate the association of other comorbidities with the most common complaints of the endometriosis (dysmenorrhea, deep dyspareunia, noncyclic pelvic pain and infertility), like autoimmune diseases (systemic lupus erythematous, rheumatoid arthritis, among others), 10e12 ovarian cancer, 10e14 psychiatric disorders (depression, anxiety, among others), 15e17 atopic diseases (asthma, sinus allergic rhinitis and dermatitis), 10,12,18,19 migraine, 20e23 sleep disorders, 24 urinary functional disorders, 25 visceral syndrome (constipation or diarrhea, nausea or vomiting, among others), 26 among others. Some of these comorbidities are not associated with chronic pain, and present genetic correlation with endometriosis.…”

Section: Introductionmentioning

confidence: 99%