Endometriosis‐Like Formations in the Lymph Nodes of the Pelvic Wall

Abstract

I;roltr the Gynaecological Uepnrhwit ( A s g w t Clwisteiism, ilf. 11.). Hispebjerg Hospital, the C,'yrmecological Deparlmcnt ( S z~i c l I:elding, M . D.), Municipal Hospital, and the Kadium Stntiorr, (JQM Nidsesern, M. D.) Copenhugen

Endometriosis in para-aortic lymph nodes during pregnancy: case report and review of literature

“…Sampson proposed retrograde menstruation and peritoneal implantation in 1925; however, his theory does not explain why only 5%-10% of all women are affected by this disease (1,10). Other theories include direct invasion, peritoneal metaplasia, and lymphatic and hematogenous spread (5). Our case clearly provides support for the theory of lymphatic spread.…”

“…No articles reported para-aortic lymph node involvement. DIE, colorectal, and ileocecal endometriosis are associated with locoregional lymph node involvement, and rectovaginal endometriosis is associated with pelvic lymph node metastasis (5)(6)(7)(8)(9)(15)(16)(17)(18)(19)(20).…”

“…Although the exact pathophysiology of endometriosis remains enigmatic, theories include retrograde implantation of menstrual tissue, peritoneal metaplasia, and lymphatic and venous spread (5). Recent reports of endometriosis in regional nodes support lymphatic spread (6)(7)(8)(9).…”

Endometriosis and regional lymph node involvement in a rat model

“…Th ese lesions were described as 'glandular inclusions' [13] and 'endometriosislike formations' [14], similar to endometriosis and hence the lesions were considered endometriosis [15]. Regional lymph node involvement by endometriosis was subsequently also noted in endometriosis patients.…”