Endometriosis Patients in the Postmenopausal Period: Pre- and Postmenopausal Factors Influencing Postmenopausal Health

Abstract

Objective. To evaluate patients' health status and the course of endometriosis from the premenopausal to the postmenopausal period and evaluate influencing factors that may be relevant. Methods. Questionnaire completed by 35 postmenopausal women in whom endometriosis had been histologically confirmed premenopausally. Correlation and regression analyses were carried out to identify factors relevant to their postmenopausal health status. Results. Overall, there was clear improvement in typical endometriosis symptoms and sexual life. Clear associations (P < 0.005) were observed between premenopausal factors like physical limitations caused by the disease, impaired social contacts and psychological problems, and postmenopausal pain and impairment of sexual life. Three statistical models for assessing pain and impairment of sexual life in the postmenopausal period were calculated on the basis of clinical symptoms in the premenopausal period, with a very high degree of accuracy (P < 0.001; R 2 = 0.833/0.857/0.931). Conclusions. The results of the survey strongly suggest that physical fitness and freedom from physical restrictions, a good social environment, and psychological care in both the premenopausal and postmenopausal periods lead to marked improvements in the postmenopausal period with regard to pain, dyspareunia, and influence on sexual life in endometriosis patients.

Delivery after Operation for Deeply Infiltrating Endometriosis

“…Due to the lack of large cohort studies, the prevalence of endometriosis is still unknown [ 3 ], but it is estimated that 10 to 15 percent of women in the reproductive age are affected by the disease [ 4 ]. As endometriosis is regarded to be a condition of the premenopausal woman, its peak of prevalence coincides with a woman's reproductive period [ 5 ].…”

The use of Hormone Therapy after Surgery for Endometriosis: An Analysis

“…This suggests that endogenous estrogen even at low levels is a risk factor for some women. Endometriosis lesions contain aromatase and estrogen may stimulate prostaglandin-E synthesis, which in turn increases aromatase activity in lesions (22,(24)(25)(26)(27)(28)(29)(30).…”

Keeping an Eye on Perimenopausal and Postmenopausal Endometriosis

“…Recently, Haas et al performed a retrospective analysis of 42,079 women with surgically confirmed endometriosis in Germany and they found 1,074 (2.55%) cases in the climacteric age group (55–95 years) [8]. Moreover, in a subsequent study, Haas et al [9] found that physical fitness and freedom from physical restrictions, a good social environment and psychological care in the postmenopausal period lead to a remarkable improvement in pain, dyspareunia, and influence on sexual life in women with endometriosis.…”