Endophthalmitis isolates and antibiotic sensitivities: a 6-year review of culture-proven cases

Benz, Matthew S.; Scott, Ingrid U.; Flynn, Harry W.; Unonius, Nichard; Miller, Darlene

doi:10.1016/s0002-9394(03)00896-1

Cited by 284 publications

(189 citation statements)

References 18 publications

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“…However, this may trigger antibiotic resistance. In two previous studies, it was shown that 68% of CoNS were sensitive to third generation quinolones (10)(11) . We showed a 92%-susceptibility to ciprofloxacin in our previous report (9) .…”

Section: Discussionmentioning

confidence: 94%

Incidence of endophthalmitis after cataract surgery (2002-2008) at a Brazilian university-hospital

Melo¹,

Bispo²,

Regatieri³

et al. 2010

Arq. Bras. Oftalmol.

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Section: Discussionmentioning

confidence: 94%

Incidence of endophthalmitis after cataract surgery (2002-2008) at a Brazilian university-hospital

Melo¹,

Bispo²,

Regatieri³

et al. 2010

Arq. Bras. Oftalmol.

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“…Most published articles show a predominance of gram-positive microorganisms, ranging from 63 to 86%. [13][14][15] In a previous report from our laboratory (2000-2005), gram-positive bacteria comprised 79% of the culture-proven endophthalmitis isolates. 3 In our present and previous analyses, CoNS, Streptococcus viridans, and Staphylococcus aureus were the three most common bacteria in a descending order.…”

Section: Discussionmentioning

confidence: 94%

Microbial profile and antibiotic susceptibility of culture-positive bacterial endophthalmitis

Melo

Bispo

et al. 2011

Eye

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“…Vancomycin has been reported to have 100% effectiveness against the most common causative Gram-positive endophthalmitis organisms (Benz, et al, 2004;Recchia, et al, 2005). Amikacin and ceftazidime have approximately the same success rate against Gram-negative organisms (89%) (Han, et al, 1996).…”

Section: Therapeutic Challengesmentioning

confidence: 99%

Bacterial endophthalmitis: Therapeutic challenges and host–pathogen interactions

Callegan

Gilmore

Gregory

et al. 2007

Progress in Retinal and Eye Research

156

153

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Endophthalmitis is an infection of the posterior segment of the eye that frequently results in loss of vision. This devastating result occurs despite prompt and often aggressive therapeutic and surgical intervention. Over the past decade, research has centered on determining the bacterial and host factors involved in this potentially blinding disease. The initial focus on the bacterial factors responsible for intraocular virulence has recently expanded into analysis the inflammatory response to infection, including the molecular and cellular interactions between the pathogen and host. This review discusses the epidemiology and therapeutic challenges posed by endophthalmitis, as well as recent findings from the analysis of interactions between the host and pathogen. Based on these findings, a model for the pathogenesis of endophthalmitis is presented. A more comprehensive understanding of the molecular and cellular interactions taking place between pathogen and host during endophthalmitis will expose possible therapeutic targets designed to arrest the infection and prevent vision loss.

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Endophthalmitis isolates and antibiotic sensitivities: a 6-year review of culture-proven cases

Cited by 284 publications

References 18 publications

Incidence of endophthalmitis after cataract surgery (2002-2008) at a Brazilian university-hospital

Incidence of endophthalmitis after cataract surgery (2002-2008) at a Brazilian university-hospital

Microbial profile and antibiotic susceptibility of culture-positive bacterial endophthalmitis

Bacterial endophthalmitis: Therapeutic challenges and host–pathogen interactions

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