Endorectal and Dynamic Contrast-Enhanced MRI for Detection of Local Recurrence After Radical Prostatectomy

Casciani, Emanuele; Polettini, E; Carmenini, Enrico; Floriani, Irene; Masselli, Gabriele; Bertini, Luca; Gualdi, Gian Franco

doi:10.2214/ajr.07.3032

Cited by 151 publications

(100 citation statements)

References 29 publications

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“…Casciani et al [41] in a single centre retrospective study described the use of MRI with DCE in 46 patients previously submitted to RP and with biochemical recurrence. All patients were submitted to both endorectal MRI and DCE-MRI.…”

Section: Multiparametric Mrimentioning

confidence: 99%

Comparative analysis of multiparametric magnetic resonance and PET-CT in the management of local recurrence after radical prostatectomy for prostate cancer

Alfarone

Panebianco

Schillaci

et al. 2012

Critical Reviews in Oncology/Hematology

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Purpose\ud \ud Our aim was to assess whether multiparametric magnetic resonance and PET-CT can have a role in detecting local recurrence in patients with biochemical recurrence after radical prostatectomy.\ud \ud Methods\ud \ud We reviewed the recent international literature by carrying out a PUBMED search.\ud \ud Results\ud \ud We critically reviewed 11 recent original studies about the use of PET-CT and 5 recent studies about the use of multiparametric magnetic resonance. PET-CT has not shown significant results in terms of detection rate for local recurrence in patients with low level of PSA. Multiparametric magnetic resonance showed encouraging results to detect local recurrence in patients with low PSA and with small diameter lesions.\ud \ud Conclusions\ud \ud Currently, most important urological societies do not consider multiparametric magnetic resonance and PET-CT in the follow-up of patients with suspected local recurrence after radical prostatectomy. We can assert that multiparametric magnetic resonance seems to have excellent results in detecting local recurrence in patients submitted to radical prostatectomy and PSA < 1.5 ng/ml

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Section: Multiparametric Mrimentioning

confidence: 99%

Comparative analysis of multiparametric magnetic resonance and PET-CT in the management of local recurrence after radical prostatectomy for prostate cancer

Alfarone

Panebianco

Schillaci

et al. 2012

Critical Reviews in Oncology/Hematology

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“…A study of 70 patients at high risk of local recurrence after RP demonstrated that combined MRSI and DCE-MRI showed a high sensitivity and specificity in identifying local prostate cancer recurrence in patients with biochemical progression after RP [98] . A study of 51 patients concluded that MRI combined with DCE-MRI is an accurate method to identify local recurrence after radical prostatectomy [99] . A study concluded that prostate cancer local recurrence after radiation therapy occurs at the site of the primary tumor [100] .…”

Section: Tumor Recurrencementioning

confidence: 99%

Incremental value of magnetic resonance imaging in the advanced management of prostate cancer

Wang¹

2009

WJR

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Prostate cancer is a major public health burden throughout the world. The high incidence of prostate cancer, combined with earlier detection and downstaging at the time of diagnosis, and the slow natural progression and biological heterogeneity of the disease, has made its management a complex and controversial issue. There is growing demand for patient-specific therapies that can minimize treatment morbidity while maximizing treatment benefits. There are a number of clinical parameters and clinical nomograms to help with the choice of treatment. Magnetic resonance imaging (MRI) is a technique which makes safer, more individualized therapies possible due to high spatial resolution, superior contrast resolution, multiplanar capability, and a large field of view. Other MRI techniques such as MR spectroscopic imaging, dynamic contrast-enhanced MRI or perfusion MRI, and diffusion-weighted imaging complement MRI by reflecting tissue biochemistry, Brownian motion of water molecules, and capillary wall permeability, respectively. This editorial review highlights the incremental value of MRI in the advanced management of prostate cancer to non-invasively improve cancer staging, biologic potential, treatment planning, therapy response, local recurrence, and to guide target biopsy for clinical suspected cancer with previous negative biopsy. Finally, some future prospects for MRI in prostate cancer management are given.

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“…16 MR imaging with endorectal coil, combined with dynamic contrast-enhanced imaging, seems to have a higher sensitivity and specificity compared with MR imaging alone in detecting local recurrences after RP. 17 The application of MR imaging and nuclear medicine (positron emission/CT (PET/CT) with new tracers like 11 C or 18 F-choline and acetate) might offer a better assessment of recurrent PCa. 18 The detection rate is directly correlated to the PSA value at the time of study, with detection rates between 36 and 60% at levels below 1 and a sensitivity of approximately 80% for values up to 2.5 ng ml À1 .…”

Section: Diagnostic Evaluationmentioning

confidence: 99%

Diagnostic evaluation of PSA recurrence and review of hormonal management after radical prostatectomy

Poppel

Joniau

Cleynenbreugel

et al. 2009

Prostate Cancer Prostatic Dis

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The aim of this review is to provide a discussion of the diagnostic evaluation of biochemical recurrence following radical prostatectomy (RP) and an overview of the postoperative hormonal treatment (HT) options. As no randomized trials in the clinical setting of postoperative prostatespecific antigen recurrence have been reported, there is no conclusive evidence that HT after RP will prolong survival or reduce morbidity. Non-traditional approaches, such as intermittent androgen deprivation, non-steroidal anti-androgens and combination of finasteride and nonsteroidal anti-androgen, are investigated and may be acceptable options. Combinations of HT with radiotherapy and/or chemotherapy for treatment of recurrent prostate cancer are under study.

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Endorectal and Dynamic Contrast-Enhanced MRI for Detection of Local Recurrence After Radical Prostatectomy

Abstract: MRI combined with dynamic contrast-enhanced MRI showed a higher sensitivity and specificity compared with MRI alone in detecting local recurrences after radical prostatectomy.

Cited by 151 publications

References 29 publications

Comparative analysis of multiparametric magnetic resonance and PET-CT in the management of local recurrence after radical prostatectomy for prostate cancer

Comparative analysis of multiparametric magnetic resonance and PET-CT in the management of local recurrence after radical prostatectomy for prostate cancer

Incremental value of magnetic resonance imaging in the advanced management of prostate cancer

Diagnostic evaluation of PSA recurrence and review of hormonal management after radical prostatectomy

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