Endorsement of the Kidney Disease Improving Global Outcomes (KDIGO) guidelines on kidney transplantation: a European Renal Best Practice (ERBP) position statement

Abstract

Sra. Directora: Los pacientes renales en programa de hemodiálisis presentan una inmunidad deprimida y una mayor sus-ceptibilidad a las infecciones. La necesidad de mani-pular un punto de acceso vascular y de realizar varias sesiones semanales de circulación extracorpórea de varias horas de duración, a través de un circuito con puntos permeables a virus y bacterias, aumenta la vulnerabilidad de estos pacientes a la infección por microorganismos que contaminan los objetos exis-tentes en su entorno próximo, incluyendo los propios monitores. La epidemiología de las infecciones por virus trans-mitidos por la sangre en los pacientes que requieren hemodiálisis intermitente sigue siendo desconocida en buena medida y no se sabe con exactitud como se transmiten virus como el VHC a los pacientes en diálisis, lo que supone un riesgo constante en las mo-dernas unidades de diálisis. El contagio de los virus es objeto de especial preocupación desde el punto de vista de la enfermería preventiva. Las posibles me-didas para prevenir la transmisión de estos virus son actualmente objeto de controversia. Simulación virtual de brote epidémico en una unidad de diálisis 246 78 Rev Soc Esp Enferm Nefrol 2009; 12 (3): 245/247

Risk Models to Predict Chronic Kidney Disease and Its Progression: A Systematic Review

“…We searched relevant clinical practice guidelines to investigate the implementation of CKD prediction models in countries in which such models have been developed. In the absence of validated strategies for these types of searches, we targeted guidelines (when available in English language) compiled by a selection of organizations known to be involved in issues relating to kidney diseases, including the American Society of Nephrology (http://www.asn-online.org), the US National Kidney Foundation [12], the UK National Institute for Health and Clinical Excellence [13], the International Society of Nephrology [14], the European Renal Association–European Dialysis and Transplant [15], the Canadian Society of Nephrology [16], Kidney Disease: Improving Global Outcomes [17], The Korean Society of Nephrology (http://www.ksn.or.kr/english/), the Japanese Society for Dialysis Therapy [18], The Japan Association of Chronic Kidney Disease Initiatives (J-CKDI) [19], and the Taiwan Society of Nephrology [20].…”

Intravenous immunoglobulin therapy in kidney transplant recipients with de novo DSA: Results of an observational study

“…dn DSA are also associated with subclinical histologic lesions, which are an important determinant of graft survival [11, 12]. Thus, current recommendations are to screen for the development of dn DSA at 3 months, one year, and once a year after kidney transplant [13]. Although the pathogenicity of dn DSA has been clearly established, no preemptive strategy has been proposed so far.…”

The Peripheral NK Cell Repertoire after Kidney Transplantation is Modulated by Different Immunosuppressive Drugs

“…Although HLA-C molecules represent prominent KIR ligands, HLA-C typing is not routinely performed and rather ignored along with HLA-DQ and HLA-DP molecules for the allocation of kidneys from deceased donors to renal insufficient patients. The standard immunosuppressive regimen, also at our transplantation unit is based on initial CNI, either cyclosporine A (CsA) or Tacrolimus (Tac) in combination with steroids (prednisolone) and mycophenolate mofetil (MMF) (Heemann et al, 2011). Once treated with this CNI-based regimen, minimization of the drug is associated with a higher risk of rejection.…”