Endoscopic and pathologic features of esophageal lymphoma: a report of four cases in patients with acquired immune deficiency syndrome

Primary esophageal diffuse large B-cell lymphoma: Report of a case

“…Radiographic and endoscopic fi ndings of esophageal lymphoma are non-specifi c, and usually include an intramural mass, varicoid stenosis, strictures, multiple submucosal nodules, or a polypoid protrusion with or without ulceration. [7][8][9][10][11] These fi ndings are frequently interpreted as benign disease, and the stricture formation can be very similar to that caused by the schirrhous type of carcinoma. 12 Endoscopically, the presence of an intact mucosa, circumferential esophageal involvement, and a schirrhous type of tumor mass, which were all seen in this case and in the case reported by Salerno et al, 13 suggests a possible diagnosis of lymphoma.…”

Diagnosis and treatment of esophagitis in AIDS

“…The presence of tracheo-esophageal fistulas, ulcerated malignant-appearing mass(es), polypoid-appearing lesion(s), and atypical strictures should suggest the possibility of tuberculosis, MAC, or tumors such as lymphoma and Kaposi sarcoma. 10,21,22 On endoscopy, Kaposi sarcoma appears as multiple violaceous-red macular or plaque-like nodules. With tumor progression, the lesions become nodular or confluent, resulting in a mass lesion.…”

“…10 The size of the lesion(s) is variable from 1 cm to extensive disease, resulting in complete luminal obstruction. 10 Squamous cell carcinoma and Barrett's associated adenocarcinoma have also been described in these patients and appear as typical mass lesions.…”

Primary Esophageal Lymphoma in AIDS

“…Primary esophageal lymphoma is even more rare, with fewer than 15 cases reported in the general population5-7 and 6 cases reported in HIV-infected patients. [8][9][10][11] Criteria that distinguish between primary and secondary gastrointestinal tract lymphomas were described by Dawson et al12 A gastrointestinal lymphoma is considered primary when the patient has no palpable superficial lymph nodes, no enlargement of mediastinal lymph nodes on chest radiograph, normal white blood cell count and differential, an alimentary lesion that predominates with lymph node involvement, if any, confined to the drainage area of the involved segment of the gut, and no involvement of the liver or spleen. Table 1 summarizes the main characteristics of patients with HIV infection and primary esophageal lymphoma.…”