Endoscopic evaluation of dyspeptic patients

Ghosh, Dipankar; Barua, U K; Sk, Saha; Ghosh, C K; Rahman, Md. Mustafizur; Alam, Mahtab

doi:10.3329/bmj.v42i3.19001

Cited by 3 publications

(5 citation statements)

References 8 publications

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“…03% duodenal ulcer, 02% reflux oesophagitis, and carcinoma stomach rare 01%.This study is almost comparable to the findings of Ghosh D et alstudy16 conducted in Bangladesh.Overall findings of endoscopy of upper GIT were 55.6% normal, 8.3% reflux oesophagitis, 22.2% gastric erosions, 2.8% gastric ulcer, 5.6% duodenal erosions and 5.7% duodenal ulcer . In another study, Zagari R et al reported that out of 1,033 study population, endoscopic findings was normal in 76.8%.…”

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confidence: 85%

Endoscopic Evaluation of Dyspeptic Patient in Tertiary Care Hospital

Hasan

Noman

Hayat³

et al. 2021

Bangla J Med

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Objectives: To observe the organic change occurs in dyspeptic patient by upper gastrointestinal endoscopy. Methods: The present prospective, observational, cross-sectional study was conducted at Medicine and Gastroenterology department of Sir Salimullah Medical College & Mitford Hospital, over a period of 6 month from 2019 to 2020.The study population was 200with aged18 years and above, irrespective of sex and who were suffering from dyspeptic symptoms for at least 6 months duration. Data regarding the demographic profile of study population nand endoscopic findings were processed and analyzed using software SPSS (Statistical Package for social science) version 26. Results: It was observed that most of the dyspeptic patients 71%were showing normal endoscopic findings and 29% have abnormal endoscopy findingwhere majority of the patient were 51 – 70 years of age.Out of them 41% of male and 26% of female had organic changes. It was also found that 46% of the patients were smoker and among them 34(37%) had abnormal endoscopic finding where 24(22%) non-smokerpatient had abnormal finding, which were statistically significant (p,0.05) between two group. Among abnormal endoscopic finding, 11% gastric erosions, 08% gastric ulcer, 04% duodenal erosions, 03% duodenal ulcer, 02% reflux oesophagitis, and carcinoma stomach rare 01%. Conclusion: The study concludes that majority of patients with complaints of dyspepsia have no organic lesion and can be considered non ulcer dyspepsia. The common abnormal endoscopic findings included gastric erosion and gastric ulcers relating to dyspepsia. The study findings also suggest that smoking is a risk factor for developing organic changes in dyspeptic patients specially in middle age group. Bangladesh J Medicine July 2022; 33(1) : 3-7

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confidence: 85%

Endoscopic Evaluation of Dyspeptic Patient in Tertiary Care Hospital

Hasan

Noman

Hayat³

et al. 2021

Bangla J Med

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“…24 In the present study majority (n=197, 64.8%) of the patients were below 40 years which is consistent with previous studies. 4,5,14 Like previous studies upper abdominal pain (45.7%) and or burning (36.2%) were the most prevalent dyspeptic symptoms. 1,5,17,25 Around 63.5% of our patients had one or more alarm symptoms.…”

Section: Discussionsupporting

confidence: 50%

“…1,22,23 Around 44-65% of our dyspeptic patients have one or more organic lesions in upper GI endoscopy; however, the prevalence of serious organic lesions is low. 4,5 H. pylori infection, infection-associated dyspeptic symptoms and related endoscopic lesions are prevalent in Bangladesh. 24 In the present study majority (n=197, 64.8%) of the patients were below 40 years which is consistent with previous studies.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3] However, most of the dyspeptic patients do not have a major organic lesion in endoscopy. [4][5][6][7] Endoscopy is the most accurate way to diagnose most organic lesions responsible for dyspepsia. A randomized controlled trial proved cost effectiveness and less loss of working days associated with initial endoscopy and directed treatment rather than empiric therapy with H 2 receptor blockers.…”

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confidence: 99%

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Value of Alarm Features in Dyspepsia for Predicting Significant Organic Lesions in Endoscopy

Perveen¹,

Saha

Salam

2023

J. Bangladesh Coll. Phys.

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Background: For a long older age and the presence of alarm features are regarded as indications for prompt endoscopy in patients with dyspepsia. We aimed to find out the value of alarm features in diagnosing serious organic upper gastrointestinal lesions in patients with dyspepsia. Material & methods: In this observational study clinical variables and endoscopic findings of consecutive patients with dyspepsia were recorded in a semi-structured questionnaire. Univariate and multivariate logistic regression was done stepwise to identify predictors for endoscopic findings. A simplified predictor model was built with the age and the presence of any predictor alarm feature to find out the diagnostic accuracy of this model for the significant endoscopic lesion. Results: Among 304 patients (M=134, F=170) one or more alarm features were present in 193 cases (63.5%). Significant organic lesions were found in 84(27.6%) cases. Age ≥ 45 years (OR 2.608), abdominal lump (OR 4.489) and family history of upper gastrointestinal cancer (OR 3.880) were found as independent predictors of major endoscopic findings. Using a simplified predictor model of age ≥ 45 years or the presence of any predictive alarm feature, sensitivity, specificity, positive predictive value, and negative predictive value were 32.4 %, 82.5 %, 79.8% and 36.4% respectively for a significant endoscopic lesion. For upper gastrointestinal cancers, these values were 6%, 100.0%, 100.0% and 47.3% respectively. Conclusion: The predictive value of the age and the presence of alarm features alone are not optimal for significant endoscopic findings in patients with dyspepsia. A newer and more accurate predictive model is a time demand for organic UGI lesions, especially for malignancies. J Bangladesh Coll Phys Surg 2023; 41: 132-140

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“…Saheed Shurawardy Hospital by Ghosh et al showed 55.6% of the patients had normal endoscopic study 11. Whereas almost similar finding were found by Islam et al study, where they found 58.14% subjects had normal gastro-…”

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confidence: 56%

Prevalance and association of Helicobater Pylori with gastro-duodenal mucosal lesions in patients with dyspepsia

Siddique¹,

Hossain²,

Rana

et al. 2020

J Dhaka Med Coll

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Helicobacter Pylori a very common worldwide infection is responsible for number of upper GIT lesions like gastritis, peptic ulcer disease, gastric carcinoma and mucosa associated lymphoid tissue lymphoma. On the other hand, dyspepsia is a wide spectrum of nonspecific upper GIT symptoms for which patients very frequently visit gastroenterology clinics. The objective of the study was to find prevalence of Helicobacter Pylori among the patients with dyspeptic symptoms who had gastro-duodenal mucosal lesions on upper GIT endoscopy and also if there is any association between these two variables. 164 cases of dyspepsia were done index upper GIT endoscopy as per inclusion and exclusion criteria from April 2018 to December 2018 in Seikh Sayera Khatun Medical College Hospital, Gopalganj. Two gastric biopsies (from antrum and body) were taken and immediately placed in a commercial RUT (rapid urease test) kit. Positive test (rapid urease test) was indicated by change in the color of the kit from yellow to pink or red within 24 hours. Out of 164 patients, 62 (37.8%) patients had gastro-duodenal mucosal lesions and rest(62.2%) showed normal upper GIT at endoscopy. Among the 62 patients highest (38) number of the patients endoscopy showed gastritis and least (3) showed gastric ulcer. Among 62 patients with endoscopic gastro-duodenal mucosal lesions, 36 patients were infected with Helicobacter Pylori. On the contrary 27 patients out of 102 subjects who had normal upper GIT at endoscopy recorded infected with Helicobacter Pylori. Statistically analysis was done using chi-square test with the help of SPSS software windows version 25. The level of statistical significance was set at 0.05. In our study it was observed that statistically there was significant relation of Helicobacter Pylori with gastro-duodenal mucosal lesions as P value was less than 0.05. In this study, we found that Helicobacter Pylori was significantly associated with gastro-duodenal mucosal lesions among the patients with dyspeptic symptoms. So, our suggestion will be to confirm H. pylori infection if anybody has gastro-duodenal mucosal lesions if a subject does upper GIT endoscopy for dyspeptic symptoms. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 100-104

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Endoscopic evaluation of dyspeptic patients

Cited by 3 publications

References 8 publications

Endoscopic Evaluation of Dyspeptic Patient in Tertiary Care Hospital

Endoscopic Evaluation of Dyspeptic Patient in Tertiary Care Hospital

Value of Alarm Features in Dyspepsia for Predicting Significant Organic Lesions in Endoscopy

Prevalance and association of Helicobater Pylori with gastro-duodenal mucosal lesions in patients with dyspepsia

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