Endoscopic Features of Gastroduodenal Crohn's Disease

Danzi, J. Thomas; Farmer, Richard G.; Sullivan, B.H.; Rankin, George B.

doi:10.1016/s0016-5085(76)80395-2

Cited by 99 publications

(29 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the transmural nature of the process cannot be assessed accurately from the superficial mucosal biopsies obtained by esophagosc~py. Such specimens often show evidence of chronic inflammation of the esophageal mucosa and submucosa without revealing its specific etiology [3,4,9,13,18]. The presence of gastric mucosa in the biopsy of the esophageal stricture of our second patient was interesting and suggested an association with Barrett's esophagus.…”

Section: Discussionmentioning

confidence: 82%

Esophageal manifestations of Crohn's disease

Ghahremani

Gore

Breuer

et al. 1982

Gastrointest Radiol

View full text Add to dashboard Cite

Two patients with concurrent esophagitis and ileocolitis due to Crohn's disease are presented. The initial feature of esophageal involvement was dysphagia caused by severe inflammation of the distal esophagus with mucosal ulcerations and polypoid folds. Long-term observation of both cases revealed a gradually progressive course leading to development of rigid esophageal structure, intramural sinus tract, and esophagobronchial or esophagogastric fistulas. The clinical and radiographic manifestations of Crohn's esophagitis in these 2 patients and in 18 previously reported cases are reviewed.

show abstract

Section: Discussionmentioning

confidence: 82%

Esophageal manifestations of Crohn's disease

Ghahremani

Gore

Breuer

et al. 1982

Gastrointest Radiol

View full text Add to dashboard Cite

show abstract

“…4 The Japanese literature has reported a high incidence of incipient microlesions in the stomach and duodenum (50%-90% 5 ), in Crohn's disease whereas progressive gastroduodenal lesions of Crohn's disease causing upper gastrointestinal stenosis occur at a low incidence (0.5%-4%) in Western countries. 4,[6][7][8][9][10][11] Thirty-seven patients with Crohn's disease with gastric and duodenal lesions have been reported in Japan. [1][2][3][12][13][14][15][16][17][18] Endoscopy revealed stenosis of the pyloric ring in 16, ulceration in 11, nodular protrusions in 8, cobblestone changes in 6, and shallow erosions in 5.…”

Section: Discussionmentioning

confidence: 99%

“…[6][7][8][9][10][11] When lesions of the small and large bowel are already evident, diagnosis of the gastroduodenal lesions of Crohn's disease is relatively easy. However, if only gastric or duodenal lesions are present, it is necessary to differentiate this condition from several other diseases.…”

Section: Discussionmentioning

confidence: 99%

“…However, if only gastric or duodenal lesions are present, it is necessary to differentiate this condition from several other diseases. 7 Peptic ulcer is often associated with Crohn's disease, 2 although gastric acid secretion may vary from low to high. [10][11][12] A low acid output tends to occur in advanced disease associated with extensive gastric mucosal destruction, and a change in acidity appears to occur as the lesions progress.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pyloric stenosis due to Crohn's disease

Nakamura

Yanai

Miura³

et al. 1998

Journal of Gastroenterology

View full text Add to dashboard Cite

Gastroduodenal involvement by Crohn's disease is relatively rare and occasionally causes pyloric stenosis, for which medical therapy may be ineffective and surgery may be required. We report on a 44-year-old man patient in whom corticosteroids had a marked effect in reducing pyloric stenosis caused by Crohn's disease. A proton-pump inhibitor was not effective, and Helicobacter pylori was negative.

show abstract

“…lymphoma, and infection or foreign body reaction that causes granulomatous infiltration of the stomach or duodenum. 17 Bagby and colleagues 7 described a patient with pancreatitis in whom inflammation and edema of the second portion of the duodenum simulated Crohn's disease radiographically; the radiographic abnormalities resolved completely after two weeks as the pancreatitis resolved.…”

mentioning

confidence: 99%

Gastroduodenal Crohn's disease

Harary¹,

Rogers²

1983

Postgraduate Medicine

View full text Add to dashboard Cite

Gastroduodenal Crohn's disease usually, but not always, occurs in patients with previously established ileal and/or colonic Crohn's disease. Symptoms include postprandial epigastric pain accompanied by nausea and sometimes vomiting, weight loss, anorexia, bloating, and diarrhea. Obstruction is the most common complication. Diagnosis can usually be made radiographically or endoscopically. Certain radiographic patterns are almost diagnostic, eg, obliteration of a distinct pyloric channel and a rigidly narrowed antrum tapering into a diseased duodenal bulb. Endoscopic mucosal biopsy of abnormal areas almost always shows chronic inflammation, although granulomas are not common. In patients with symptoms other than intractable obstruction, medical management, such as intermittent corticosteroid therapy, should be attempted. Surgery is usually indicated for refractory obstruction; gastrojejunostomy is the preferred approach.

show abstract

Endoscopic Features of Gastroduodenal Crohn's Disease

Cited by 99 publications

References 23 publications

Esophageal manifestations of Crohn's disease

Esophageal manifestations of Crohn's disease

Pyloric stenosis due to Crohn's disease

Gastroduodenal Crohn's disease

Contact Info

Product

Resources

About