Endoscopic full-thickness resection (eFTR) in colon and rectum: indications and outcomes in the first 37 cases in a single center

Høgh, Anders; Deding, Ulrik; Bjørsum-Meyer, Thomas; Buch, Niels; Baatrup, Gunnar

doi:10.1007/s00464-022-09263-1

Cited by 5 publications

(3 citation statements)

References 16 publications

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“…Twenty‐nine studies with 3467 patients (2045 [59%] male patients) and 3492 lesions were included in this systematic review and meta‐analysis 11–39 . The PRISMA flowchart of the study selection process is provided (Fig.…”

Section: Resultsmentioning

confidence: 99%

Device‐assisted endoscopic full‐thickness resection in colorectum: Systematic review and meta‐analysis

Nabi

Samanta

Dhar

et al. 2023

Digestive Endoscopy

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ObjectivesEndoscopic full‐thickness resection (EFTR) is emerging as an effective modality for mucosal and submucosal lesions in the colorectum. In this systematic review and meta‐analysis, we aimed to analyze the success and safety of device‐assisted EFTR in the colon and rectum.MethodsA literature search was performed in the Embase, PubMed, and Medline databases for studies evaluating device‐assisted EFTR between inception to October 2022. The primary outcome of the study was clinical success (R0 resection) with EFTR. Secondary outcomes included technical success, procedure duration, and adverse events.ResultsIn all, 29 studies with 3467 patients (59% male patients, 3492 lesions) were included in the analysis. The lesions were located in right colon (47.5%), left colon (28.6%), and rectum (24.3%). EFTR was performed for subepithelial lesions in 7.2% patients. The pooled mean size of the lesions was 16.6 mm (95% confidence interval [CI] 14.9–18.2, I2 98%). Technical success was achieved in 87.1% (95% CI 85.1–88.9%, I2 39%) procedures. The pooled rate of en bloc resection was 88.1% (95% CI 86–90%, I2 47%) and R0 resection was 81.8% (95% CI 79–84.3%, I2 56%). In subepithelial lesions, the pooled rate of R0 resection was 94.3% (95% CI 89.7–96.9%, I2 0%). The pooled rate of adverse events was 11.9% (95% CI 10.2–13.9%, I2 43%) and major adverse events requiring surgery was 2.5% (95% CI 2.0–3.1%, I2 0%).ConclusionDevice‐assisted EFTR is a safe and effective treatment modality in cases with adenomatous and subepithelial colorectal lesions. Comparative studies are required with conventional resection techniques, including endoscopic mucosal resection and submucosal dissection.

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Section: Resultsmentioning

confidence: 99%

Device‐assisted endoscopic full‐thickness resection in colorectum: Systematic review and meta‐analysis

Nabi

Samanta

Dhar

et al. 2023

Digestive Endoscopy

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“…In cases where there is submucosal fibrosis or a polyp extends beyond the superficial submucosa, EMR and ESD should be avoided given their higher risk of complications. Although these lesions historically required surgery, recent advancement in endoscopic techniques introduced endoscopic full-thickness resection (EFTR) as a minimally invasive alternative to resect these lesions [ 33 ]. The technique involves full thickness resection of the mucosa including the muscularis propria, employing either an exposed or non-exposed approach.…”

Section: Large Polyp Removalmentioning

confidence: 99%

Endoscopic techniques for management of large colorectal polyps, strictures and leaks

Gordon,

Eichenwald,

Systrom

2024

Surgery Open Science

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“…This could potentially enable far more patients access to ESD as well as more complicated procedures such as endoscopic full-thickness resection (EFTR), among others. 20 21…”

Section: Future Of Robotic Endoscopic Surgerymentioning

confidence: 99%

Robotic Transanal Minimally Invasive Surgery for Rectal Polyps

Friedman,

Rodriguez

2023

Clin Colon Rectal Surg

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Transanal minimally invasive surgery (TAMIS) can be utilized to manage a wide variety of rectal lesions but can be technically demanding with traditional laparoscopic equipment. Robotic platforms such as the da Vinci Single Port system can reduce the technical barriers of TAMIS and allow more complicated lesions to be addressed. Robotic TAMIS with the SP system follows similar indications for local excision of benign and malignant lesions as conventional TAMIS or even transanal endoscopic microsurgery. We describe our initial experience using the SP system and provide technical suggestions for how to incorporate this technology. We also address innovations in flexible endoscopic robotic surgery that we anticipate will allow for increased use of organ preservation of the colon and rectum, as well as possibly expand the use of natural orifice surgery.

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Endoscopic full-thickness resection (eFTR) in colon and rectum: indications and outcomes in the first 37 cases in a single center

Cited by 5 publications

References 16 publications

Device‐assisted endoscopic full‐thickness resection in colorectum: Systematic review and meta‐analysis

Device‐assisted endoscopic full‐thickness resection in colorectum: Systematic review and meta‐analysis

Endoscopic techniques for management of large colorectal polyps, strictures and leaks

Robotic Transanal Minimally Invasive Surgery for Rectal Polyps

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