Endoscopic full-thickness resection of a submucosal right colon lesion

Salerno, Raffaele; Gherardi, Giorgio; Paternò, Emanuela; Ardizzone, Sandro

doi:10.1055/s-0042-120338

Cited by 5 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, in 1 patient, FTR was performed due to a neuroendocrine tumor with submucosal infiltration and in 1 patient with a location of an adenoma in direct proximity to a diverticulum. As shown in these cases and also confirmed in other case series 10 11 12 18 21 22 , utilization of FTR techniques might well go beyond non-lifting lesion and extend to submucosal lesions or those in complicated anatomy with involvement of diverticula or the appendix. Further, our report is the first to describe repeat FTR at the same anatomical site due to recurrent adenoma.…”

Section: Discussionsupporting

confidence: 83%

Endoscopic full-thickness resection with an over-the-scope clip device (FTRD) in the colorectum: results from a university tertiary referral center

et al. 2018

View full text Add to dashboard Cite

Background and study aims The full-thickness resection device (FTRD) represents a novel endoscopic treatment method for lesions unresectable with conventional endoscopic techniques. The overall aim of this study was to evaluate technical success and in toto resection rates, recurrence rates, as well as immediate or late complications in patients who underwent polyp removal with the FTRD. Patients and methods Data from a prospectively collected database of 12 patients who underwent 13 over-the-scope clip-based full-thickness resections between June 2015 and June 2017 were analyzed. Follow-up endoscopy was performed in 11 out of 12 patients. Results 13 full-thickness resections were performed in 7 males and 5 females (mean age 64.3 ± 6.3 years). Mean size of the lesions removed with FTRD was 17 ± 4 mm. Location was rectum (n = 6), cecum (n = 2), ascending colon (n = 2), left flexure (n = 1) and right flexure (n = 2). Mean procedure time was 68 ± 35 minutes and mean hospital stay was 2.5 ± 1.2 days. 2 patients developed post-polypectomy syndrome, which resolved after conservative treatment. No perforations and no immediate surgical revision were needed. Histology of the 13 lesions removed with FTRD showed 5 adenomas with low grade intraepithelial neoplasia (IEN), 4 high grade IEN, 1 fibrosis, 1 fibrosis without dysplasia and 2 adenocarcinomas. Technical success was achieved in all procedures (13/13, 100 %). R0 resection was achieved in 10/12 patients (83.3 %). 2 patients underwent surgery because of recurrence or not evaluable margins. In 1 patient no residual malignancy was proven in histological examination, in the other patient residual low grade IEN adenoma. Conclusion FTRD is a minimally invasive approach with good success rate of complete resection and minimal side effects.

show abstract

Section: Discussionsupporting

confidence: 83%

Endoscopic full-thickness resection with an over-the-scope clip device (FTRD) in the colorectum: results from a university tertiary referral center

et al. 2018

View full text Add to dashboard Cite

show abstract

“…94 Apart from stomach, there are reports of EFTR for SELs in esophagus, duodenum, and colon ►Table 5. 37,46,95,96 Lesions >35 mm, large extramural component, systemic spread, GI surgery or stenosis impeding insertion of EFTR device are contraindications of non-exposed EFTR for SELs. 97…”

Section: Ftrd Gist and Other Subepithelial Lesionsmentioning

confidence: 99%

Endoscopic Full Thickness Resection: A Systematic Review

Pal

Ramchandani

Inavolu

et al. 2022

Journal of Digestive Endoscopy

View full text Add to dashboard Cite

Background Endoscopic full thickness resection (EFTR) is an emerging therapeutic option for resecting subepithelial lesions (SELs) and epithelial neoplasms. We aimed to systematically review the techniques, applications, outcomes, and complications of EFTR. Methods A systematic literature search was performed using PubMed. All relevant original research articles involving EFTR were included for the review along with case report/series describing novel/rare techniques from 2001 to February 2022. Results After screening 7,739 citations, finally 141 references were included. Non-exposed EFTR has lower probability of peritoneal contamination or tumor seeding compared with exposed EFTR. Among exposed EFTR, tunneled variety is associated with lower risk of peritoneal seeding or contamination compared with non-tunneled approach. Closure techniques involve though the scope (TTS) clips, loop and clips, over the scope clips (OTSC), full thickness resection device (FTRD), and endoscopic suturing/plicating/stapling devices. The indications of EFTR range from esophagus to rectum and include SELs arising from muscularis propria (MP), non-lifting adenoma, recurrent adenoma, and even early gastric cancer (EGC) or superficial colorectal carcinoma. Other indications include difficult locations (involving appendicular orifice or diverticulum) and full thickness biopsy for motility disorders. The main limitation of FTRD is feasibility in smaller lesions (<20–25 mm), which can be circumvented by hybrid EFTR techniques. Oncologic resection with lymphadencetomy for superficial GI malignancy can be accomplished by hybrid natural orifice transluminal endoscopic surgery (NOTES) combining EFTR and NOTES. Bleeding, perforation, appendicitis, enterocolonic fistula, FTRD malfunction, peritoneal tumor seeding, and contamination are among various adverse events. Post OTSC artifacts need to be differentiated from recurrent/residual lesions to avoid re-FTRD/surgery. Conclusion EFTR is safe and effective therapeutic option for SELs, recurrent and non-lifting adenomas, tumors in difficult locations and selected cases of superficial GI carcinoma.

show abstract

Endoscopic Full-Thickness Resection for Colorectal Neoplasm: Current Status and Future Directions

Fujihara

Mori

Kobara

et al. 2018

Curr Colorectal Cancer Rep

View full text Add to dashboard Cite

Endoscopic full-thickness resection of a submucosal right colon lesion

Abstract: Use of a novel over-the-scope device to perform endoscopic full-thickness resection of a submucosal right colon lesion.Salerno Raffaele et al. EFTR of a submucosal right colon lesion … Endoscopy 2016; 48: E376-E377

Cited by 5 publications

References 3 publications

Endoscopic full-thickness resection with an over-the-scope clip device (FTRD) in the colorectum: results from a university tertiary referral center

Endoscopic full-thickness resection with an over-the-scope clip device (FTRD) in the colorectum: results from a university tertiary referral center

Endoscopic Full Thickness Resection: A Systematic Review

Endoscopic Full-Thickness Resection for Colorectal Neoplasm: Current Status and Future Directions

Contact Info

Product

Resources

About