Endoscopic Hemostasis for Non-Variceal Upper Gastrointestinal Bleeding: New Frontiers

Kichler, Adam J.; Jang, Sunguk

doi:10.5946/ce.2018.103

Cited by 18 publications

(13 citation statements)

References 44 publications

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“…8 Lasers generate heat and cause edema in the vessel wall, resulting in hemostasis. 9 Therefore, attempts have been made to reduce the risk of bleeding associated with these laser properties by using several types of lasers, including carbon dioxide (CO 2 ) laser, 10,11 Nd: YAG laser, 12 thulium laser, 13 and diode laser, 14 for endoscopic procedures.…”

Section: Diode Laser-can It Replace the Electrical Current Used In Endoscopic Submucosal Dissection? (With Video)mentioning

confidence: 99%

Diode Laser—Can It Replace the Electrical Current Used in Endoscopic Submucosal Dissection? (with Video)

Jung

Baik

et al. 2021

Clin Endosc

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Background/Aims: A new medical fiber-guided diode laser system (FDLS) is expected to offer high-precision cutting with simultaneous hemostasis. Thus, this study aimed to evaluate the feasibility of using the 1,940-nm FDLS to perform endoscopic submucosal dissection (ESD) in the gastrointestinal tract of an animal model. Methods: In this prospective animal pilot study, gastric and colorectal ESD using the FDLS was performed in ex vivo and in vivo porcine models. The completeness of en bloc resection, the procedure time, intraprocedural bleeding, histological injuries to the muscularis propria (MP) layer, and perforation were assessed. Results: The en bloc resection and perforation rates in the ex vivo study were 100% (10/10) and 10% (1/10), respectively; those in the in vivo study were 100% (4/4) and 0% for gastric ESD and 100% (4/4) and 25% (1/4) for rectal ESD, respectively. Deep MP layer injuries tended to occur more frequently in the rectal than in the gastric ESD cases, and no intraprocedural bleeding occurred in either group. Conclusions: The 1,940-nm FDLS was capable of yielding high en bloc resection rates without intraprocedural bleeding during gastric and colorectal ESD in animal models. Clin Endosc 2021 Jan 13. [Epub ahead of print]

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Section: Diode Laser-can It Replace the Electrical Current Used In Endoscopic Submucosal Dissection? (With Video)mentioning

confidence: 99%

Diode Laser—Can It Replace the Electrical Current Used in Endoscopic Submucosal Dissection? (with Video)

Jung

Baik

et al. 2021

Clin Endosc

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“…In recent years, endoscopic tools for achieving hemostasis have evolved, with a progressive increase of the success rate of therapeutic maneuvers. Novel technologies have been developed (i.e., new rotatable clips, Over-the-scope-clips (OTSC) clipping system, Padlock TM clips), and new hemostatic agents have been introduced in clinical practice (i.e., hemostatic powders or a novel self-assembling matrix-forming gel) [5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Endoscopic Ultrasound-Guided Treatments for Non-Variceal Upper GI Bleeding: A Review of the Literature

Angelis

Valdivia

Rizza

et al. 2020

JCM

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Endoscopic injection of glues, clotting factors, or sclerosing agents is a well-known therapy for the treatment of non-variceal upper gastrointestinal bleeding (NVUGIB), but less is known about endoscopic ultrasound (EUS)-guided treatments. In this setting, literature data are scarce, and no randomized controlled trials are available. We performed a review of the existing literature in order to evaluate the role of EUS-guided therapies in the management of NVUGIB. The most common treated lesions were Dieulafoy's lesions, pancreatic pseudoaneurysms, and gastrointestinal stromal tumors (GISTs). Mostly, the treatments were performed as a salvage option after failure of conventional endoscopic hemostatic attempts, showing good efficacy and a good safety profile, also documented by Doppler monitoring of treated lesions. EUS-guided therapies may be an effective option in the treatment of refractory NVUGIB, thus avoiding radiological or surgical management. Nevertheless, available literature still lacks robust data.

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“…Проблема гострих виразкових гастродуоденальних кровотеч (ВГДК) залишається однією з найактуальніших у сучасній ургентній хірургії. Кількість ВГДК за останні 7 років збільшилася на 9,7-30 %, число госпіталізованих хворих із цим ускладненням -на 56 % [1,2]. У даний час відсутня єдина думка про перевагу того чи іншого способу ендоскопічного гемостазу при ВГДК.…”

Section: вступunclassified

“…У даний час відсутня єдина думка про перевагу того чи іншого способу ендоскопічного гемостазу при ВГДК. Світова статистика свідчить, що достовірно значущою перевагою відзначається поєднання ін'єкційних і термокоагуляціонних методів ендоскопічного гемостазу [2,3]. При всьому різноманітті ендоскопічних втручань жодне з них не позбавлене недоліків і обмежень.…”

Section: вступunclassified

“…При всьому різноманітті ендоскопічних втручань жодне з них не позбавлене недоліків і обмежень. Сумніви у перевагах будь-якого способу ендоскопічного гемостазу висловлюють багато хірургів, які вважають, що за основними показниками ефективності всі ендоскопічні методи мають рівні можливості щодо зупинки і профілактики рецидивів виразкової кровотечі, а також рівною мірою безпеки [2,4,5].…”

Section: вступunclassified

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Application of Modern Methods of Endoscopic Hаemostasis in the Treatment of Gastroduodenal Ulcer Bleeding

Honcharova¹,

Svirepo²,

Honcharov³

2021

Khark. Surg. Sch.

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Summary. The aim of the study is to improve the results of treatment of patients with ulcerative gastroduodenal bleeding by using the methods of endoscopic hаemostasis. Materials and research methods. The results of endoscopic hаemostasis of 153 patients who were treated in the surgical department of the “Regional Clinical Hospital” were analyzed. Patients were examined clinically, laboratory and instrumental. Results and its discussion. For Forrest 1a, b bleeding, endoscopic clipping was used in 16 (10.4 %) patients with a visualized vessel in the bottom of the ulcer. In the studied patients of this group, there were no relapses of bleeding. Diathermy coagulation was used in 42 (27.5 %) patients. Recurrent bleeding was observed in 6 patients. Submucosal infiltration was performed in 37 (24.2 %) patients with ulcerative bleeding. Repeated bleeding was recorded in 9 patients within the next 3 hours after the intervention and in 7 patients during the first days after endoscopic hаemostasis. Combinations of endoscopic methods of hаemostasis were used in 58 (37.9 %) patients. Conclusions. The use of modern methods of endoscopic hаemostasis followed by adequate pharmacotherapy in most cases allows achieving a final stop of bleeding. Patients with a high risk of recurrent bleeding and a low surgical and anesthetic risk after successful endoscopic hаemostasis are shown surgical intervention before the development of recurrent bleeding.

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Endoscopic Hemostasis for Non-Variceal Upper Gastrointestinal Bleeding: New Frontiers

Cited by 18 publications

References 44 publications

Diode Laser—Can It Replace the Electrical Current Used in Endoscopic Submucosal Dissection? (with Video)

Diode Laser—Can It Replace the Electrical Current Used in Endoscopic Submucosal Dissection? (with Video)

Endoscopic Ultrasound-Guided Treatments for Non-Variceal Upper GI Bleeding: A Review of the Literature

Application of Modern Methods of Endoscopic Hаemostasis in the Treatment of Gastroduodenal Ulcer Bleeding

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