Endoscopic injections of Teflon to treat urinary incontinence in women.

Schulman, Claude; Simon, Jonathan; Wespes, Eric; Germeau, F

doi:10.1136/bmj.288.6412.192

Cited by 38 publications

(3 citation statements)

References 4 publications

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“…Teflon paste injection has been used since 1963 for enlargement of displaced or deformed vocal cords (Arnold, 1963) and since 1974 periurethrally to treat urinary incontinence (Politano, 1982;Schulman et al, 1984). No untoward side-effects from these uses of the paste in humans have been reported.…”

Section: Discussionmentioning

confidence: 98%

Endoscopic correction of vesico-ureteric reflux by subureteric Teflon injection: follow-up ultrasound and voiding cystography

Blake¹,

O’Connell²

1989

The British Journal of Radiology

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The technique of subureteric Teflon injection for the correction of vesico-ureteric reflux was first described by Puri and O'Donnell in 1984. The Teflon granuloma that occurs after the injection anchors the submucosal ureter, thereby preventing reflux. This paper reviews the ultrasound and cystographic findings in 88 patients with 115 refluxing ureters followed-up for periods ranging from 3 months to 3 years. Reflux disappeared in 91 ureters (79.1%) and the degree of reflux improved in 22 ureters (19.1%). In this follow-up study, the size of the granuloma on ultrasound was assessed in relation to the number of injections, the total volume of Polytef paste used and the outcome of the procedure. A well circumscribed granuloma was seen at the orifices of 92 ureters. There was no ureteric granuloma evident in 23 ureters and Teflon plaques were found at the trigone in six patients. Complications were rare. One large granuloma caused severe obstruction requiring re-implantation. The size of the granuloma appears to depend on individual tissue reaction rather than on the other factors. The presence or the size of the granuloma bears no direct relationship to the success of the procedure.

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Section: Discussionmentioning

confidence: 98%

Endoscopic correction of vesico-ureteric reflux by subureteric Teflon injection: follow-up ultrasound and voiding cystography

Blake¹,

O’Connell²

1989

The British Journal of Radiology

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“…Politano [54][55][56] had performed periurethral injection of Teflon to alleviate incontinence for almost 20 years in numerous patients and reported no significant clinical complications from particle migration or granulomas as other authors [63,64], As demonstrated by Puri and O'Donnell [57] who experimentally induced reflux in the piglet, the polytetra fluoroethylene particles maintain their position and shape at the site of injection providing a solid backing for the intravesical ureter.…”

Section: Discussionmentioning

confidence: 88%

“…Although no clinical adverse reactions have been re ported after local injection of small quantities of Teflon despite widespread experience in over several thousands of cases, 2 cases of lipiodol-like pulmonary reactions have been described after injection of large quantities for treat ment of urinary incontinence [7,10,19,25,31,32,46,50,[63][64][65]. Cross-linked bovine collagen has been widely used in dermatology and plastic surgery and is docu mented to be safe and effective.…”

Section: ]mentioning

confidence: 99%