Endoscopic Injections of Teflon to Treat Urinary Incontinence in Women

A series of 25 women with genuine stress incontinence were treated by para-urethral injection of glutaraldehyde cross-linked collagen. The technique was simple and associated with few complications. Follow-up at 3 months revealed 20 patients (80%) to have been symptomatically improved or cured. An increase in urethral closure pressure together with a decrease in urine flow rate and increase in detrusor pressure was found post-operatively. The success rate was significantly higher (90%) in patients who had undergone previous surgery for urinary incontinence when compared with those who had had no previous surgery (73%).

Section: Department Of Urology Southmead Hospital Bristolmentioning

confidence: 99%

Para‐urethral Collagen Implantation for Female Stress Incontinence

Eckford

Abrams

1991

“…The results reported in the present series are similar to those described by Lim et al (1983) but inferior to those published by other workers (Politano, 1982;Schulman et al, 1984). One possible explanation for the differences lies in the volume of Teflon paste used.…”

Section: Discussionmentioning

confidence: 99%

“…Periurethral injection of polytetrafluoroethylene (Teflon) became established as a possible treatment for stress urinary incontinence following reports of encouraging results from Politano (1982) and Schulman et al (1984). A description of our early experience using this treatment has been published previously (Vesey et al, 1988).…”

mentioning

confidence: 99%

Periurethral Teflon for Stress Urinary Incontinence: Medium‐term Results

Harrison

Brown

O'boyle

1993

Medium-term results are presented for the periurethral injection of Teflon in the treatment of stress urinary incontinence. Follow-up data were obtained on 36 women by means of case note review and the completion of a postal questionnaire. Mean follow-up was 5.1 years. Subjective results showed 12 patients to be dry or much improved while the remaining 24 patients did not obtain significant benefit from the procedure. Repeat injections in 12 women resulted in only 3 obtaining useful improvement, while a subgroup of patients who had undergone previous procedures showed a better response. No significant complications were observed. Periurethral Teflon injection is a minor surgical procedure which can produce worthwhile improvement, although an initially good result may not be sustained with longer follow-up. This method may be advocated as treatment for poor risk patients who are unsuitable for surgery, particularly when previous attempts at formal surgical correction have been unsuccessful.

“…The procedure avoids surgery, takes about I 5 min to perform and may be done on a day basis. Injection of Polytef paste has been used since 1963 for enlargement of displaced or deformed vocal cords (Arnold, 1963) and since 1974 periurethrally to treat urinary incontinence (Politano et ul., 1974;Politano, 1982;Schulman et al, 1984). No untoward side effects from its urological or otolaryngological use in humans have been reported to date.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Correction of Vesicoureteric Reflux Secondary to Neuropathic Bladder

Puri

Guiney

1986

Eleven patients with vesicoureteric reflux secondary to neuropathic bladder were treated by endoscopic injection of pyrolised polytetrafluoroethylene (Polytef) paste. Thirteen of the 15 ureters treated showed disappearance of reflux after one injection. The amount of Polytef paste injected varied from 0.2 to 0.9 ml (mean 0.45 ml). There were no complications, except in one ureter where distension of the collecting system was slightly increased compared with the pre-operative urogram.