Endoscopic mucosal resection of large hyperplastic polyps in 3 patients with Barrett’s esophagus

Abstract

EMR-C appears to be a safe and effective method for treating benign esophageal mucosal lesions, allowing also the complete removal of SSBE.

Multiple Esophageal Hyperplastic Polyps in a Nigerian Woman

“…However, there is evidence to suggest that the lesion develops as a result of mucosal regenerative response to surrounding mucosal injury [5,6,8]. The lesion is commonly associated with erosive esophagitis/or hiatal hernia [4][5][6]8,12,13]. Other potential etiologies include eosinophilic esophagitis, Crohn's disease, medication-induced esophagitis, infection, anastomotic or polypectomy sites, photodynamic therapy, and type 1 neurofibromatosis [5,8,14,15].…”

“…A few cases of hyperplastic polyps have been found in the cervical esophagus, usually in association with ectopic gastric mucosa [4,16,17]. Polyps at the EGJ may be located at the end of a prominent inflamed gastric fold of mucosa, also known as "the sentinel fold", seen in reflux esophagitis [4,6,18].…”

“…Endoscopic snare polypectomy may be required in those that are symptomatic [23,24]. Endoscopic mucosal resection is recommended in cases that are associated with Barrett's esophagus [4]. We opted for PPI therapy in our patient with the hope that it will take care of all her problems (dyspepsia, GERD and polyps) simultaneously.…”

“…Polypoid epithelial lesions of the esophagus are rare worldwide [4,7,8]. We encountered only a report of hyperplastic polyp of the esophagus from Nigeria in our literature review [9].…”

“…They are often asymptomatic and discovered incidentally at endoscopy or radioimaging [3,4]. There are various ways of classifying benign esophageal tumors such as classification by histological cell type (epithelial and non-epithelial tumors); classification by location in the esophageal wall (intramural and extramural tumors); and classification by endoscopic appearance (flat, raised, or cystic lesions) [1,[4][5][6].…”