Endoscopic nasal versus open approach for the management of sinonasal adenocarcinoma: A pooled‐analysis of 1826 patients

Abstract

Background. Surgical resection represents the gold standard for the treatment of sinonasal malignancies. This study reviewed the published outcomes on endoscopic surgery or endoscopic-assisted surgery versus open approach for the management of sinonasal adenocarcinomas. Methods. PubMed, EMBASE, the Cochrane Library, and CENTRAL electronic databases were searched for English language articles on endoscopic surgery, endoscopic-assisted surgery, and open approach for sinonasal adenocarcinomas. Each article was examined for patient data and outcomes for analysis. Results. Thirty-nine articles including 1826 patients were used for the analysis. The endoscopic surgery and endoscopic-assisted surgery showed low rates of major complications (6.6% and 25.9%, respectively) compared to open approaches (36.4%; p < .01). The incidence of local failure was lower in the endoscopic surgery group as compared with open approach patients (17.8% vs 38.5%; p < .01, respectively). The multivariate Cox regression model showed a worst overall survival related to advanced T classification and open approach. Conclusion. From the existing body of data, there is growing evidence that endoscopic nasal resection is a safe surgical option in the management of sinonasal adenocarcinomas.

Sinonasal malignancies: Endoscopic treatment outcomes

“…Similar results were found with respect to sinonasal adenocarcinoma. A recent pooled‐analysis demonstrated improved survival outcomes for patients treated endoscopically . One thousand four hundred four cases were included from retrospective studies and crude survivals were stratified based on T classification and surgical approach (endoscopic or open).…”

“…A recent pooled-analysis demonstrated improved survival outcomes for patients treated endoscopically. 16 One thousand four hundred four cases were included from retrospective studies and crude survivals were stratified based on T classification and surgical approach (endoscopic or open). The overall local recurrence rate was 17.8% in the endoscopic surgery group compared to 38.5% in the open group.…”

Prognostic value of the seventh AJCC/UICC TNM classification of intestinal-type ethmoid adenocarcinoma: Systematic review and risk prediction model

“…The development of endoscopic surgery has revolutionized the ITAC management, therefore, opening the question of the accuracy of this classification. Meccariello et al 28 has already clearly pointed out the lower rate of morbidity in endoscopic surgery. Thus, we aimed at evaluating the outcome of patients with ITAC after surgery, and further quantifying the prognostic value of the TNM classification in this rare disease.…”

Combined Transfacial and Endoscopic Approach to Resect a Posterior Pharyngeal wall Tumour in the Setting of Absolute Trismus

“…Research to date on this subject is best summarized as involving (1) cadaveric modeling to assess the feasibility of these approaches to access the deep recesses of the midface and sub skull base [14]; (2) comprehensive meta-analysis and systematic review [15] and (3) clinical outcome studies [16].…”