Endoscopic Removal of Chondrosarcoma Originating from the Nasal Septum

Abstract

Abstract:Background: Chondrosarcomas are rare non-epithelial malignant tumours. Surgery is the primary treatment option for chondrosarcoma, with adjuvant therapy having a minor role. In cases of nasal chondrosarcoma, however, en bloc total removal by open approaches is often undesirable. Here we report a case of chondrosarcoma arising from the nasal septum, which was resected endoscopically.Case Report: The case was 50-year-old man with nasal stuffiness. Computed tomography revealed a large lesion arising from the nasal septum composed of a low-density area with scattered high-density areas. Grade I chondrosarcoma was diagnosed based on histopathological analysis. After tumour margins were carefully identified on CT images and in the nasal cavities, trans-nasal endoscopic piece-by-piece tumour removal was conducted. One year after the surgery, there was no sign of local recurrence or distant metastasis.Clinical Implication: Transnasal endoscopic removal could represent a safe and potentially curative treatment for this malignant tumour.

Chondrosarcoma of Posterior Nasal Septum

“…6 Radical surgical resection is the definitive treatment of choice for chondrosarcomas. 3,5 Various surgical approaches have been described in the literature like Weber Ferguson, sublabial-transnasal , lateral rhinotomy approach, Le Fort I downfracture and anterior cranial approach, transnasal endoscopic and microscopic approach. 1,2,4,6 The use of navigation system with endoscopic surgery has also been tried.…”