Endoscopic resection for non-polypoid dysplasia in inflammatory bowel disease: a systematic review and meta-analysis

Chen, Wei; Zhang, Yuelun; Zhao, Yongqiang; Yang, Aiming; Qian, Jiaming; Wu, Dong

doi:10.1007/s00464-020-08225-9

Cited by 11 publications

(13 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The American Society for Gastrointestinal Endoscopy also recommends en bloc resection by EMR or ESD of endoscopically visible dysplastic lesions in patients with inflammatory bowel disease (IBD) [ 51 ]. A recent meta-analysis including seven studies concluded that nonpolypoid dysplasia associated with IBD can be resected endoscopically with a low recurrence rate, especially by ESD [ 52 ].…”

Section: Endoscopic Approaches To Therapymentioning

confidence: 99%

Minimally Invasive Endoscopic and Surgical Management of Rectal Neoplasia

Ghamdi

Leeds

Fang

et al. 2022

Cancers

View full text Add to dashboard Cite

Rectal cancer demonstrates a characteristic natural history in which benign rectal neoplasia precedes malignancy. The worldwide burden of rectal cancer is significant, with rectal cancer accounting for one-third of colorectal cancer cases annually. The importance of early detection and successful management is essential in decreasing its clinical burden. Minimally invasive treatment of rectal neoplasia has evolved over the past several decades, which has led to reduced local recurrence rates and improved survival outcomes. The approach to diagnosis, staging, and selection of appropriate treatment modalities is a multidisciplinary effort combining interventional endoscopy, surgery, and radiology tools. This review examines the currently available minimally invasive endoscopic and surgical management options of rectal neoplasia.

show abstract

Section: Endoscopic Approaches To Therapymentioning

confidence: 99%

Minimally Invasive Endoscopic and Surgical Management of Rectal Neoplasia

Ghamdi

Leeds

Fang

et al. 2022

Cancers

View full text Add to dashboard Cite

show abstract

“…A systematic review and meta-analysis including 1,428 resected colonic lesions in IBD patients showed the pooled incidences of bleeding and perforation after endoscopic resection were 0.022 (95%CI 0.011-0.044) and 0.020 (95%CI 0.009-0.044), respectively[ 28 ]. Another meta-analysis revealed that the pooled rates of margin-negative (R0) and en-bloc resection rates of non-polypoid dysplasia in IBD patients were 0.70 (95%CI 0.55-0.81) and 0.86 (95%CI 0.65-0.95), respectively[ 29 ].…”

Section: Endoscopic Resection For Neoplastic Lesions In Ibdmentioning

confidence: 99%

“…A recent systematic review and meta-analysis showed the pooled risks of CRC and any dysplasia after the endoscopic resection of neoplastic lesions in IBD patients was 2 and 43 per 1,000 person-year of follow-up, respectively, suggesting the requirement of surveillance colonoscopy after the endoscopic resection[ 28 ]. Another meta-analysis including 202 IBD patients with non-polypoid dysplasia demonstrated that the pooled incidences of CRC and metachronous dysplasia after the endoscopic resection were 33 and 90 per 1,000 person-year of follow-up, respectively[ 29 ], suggesting that the likelihood of metachronous lesions would be higher in non-polypoid lesions compared with other types. These findings emphasize the critical importance of having a discussion regarding the risks and benefits of surveillance colonoscopy and colectomy with patients following endoscopic resection.…”

Section: Endoscopic Resection For Neoplastic Lesions In Ibdmentioning

confidence: 99%

Evolving roles of magnifying endoscopy and endoscopic resection for neoplasia in inflammatory bowel diseases

Akiyama¹,

Sakamoto²,

Steinberg³

et al. 2022

WJGO

View full text Add to dashboard Cite

Magnifying endoscopy is a useful technique to differentiate neoplasia from non-neoplastic lesions. Data regarding the clinical utility of magnifying endoscopy for neoplasia in patients with inflammatory bowel disease (IBD) has been emerging. While Kudo’s pit pattern types III-V are findings suggestive of neoplasia in non-IBD patients, these pit patterns are predictive of IBD-associated neoplasia as well. However, active chronic inflammatory processes, particularly regenerative changes, can mimic neoplastic pit patterns and may affect a meticulous evaluation of pit pattern diagnosis in patients with IBD. The clinical evidence regarding the utility of magnifying endoscopy with narrow band imaging or endocytoscopy has also been evolving in regard to the diagnosis of IBD-associated neoplasia. These advanced endoscopic techniques are promising for multiple reasons; not only for making an accurate diagnosis of neoplasia, but also in determining if endoscopic resection is appropriate for such lesions in patients with IBD. In this review, we discuss the diagnostic accuracy and limitations of magnifying endoscopy in assessing IBD-associated neoplasia and examine the feasibility and outcomes of endoscopic resection for these lesions.

show abstract

“…These techniques are also used to resect neoplasia but involve resecting from the mucosal and submucosal layers instead of from the muscularis propria [1]. Studies have largely found low rates of perforation, post-procedural bleeding, and the need for surgical intervention with high technical success rates [5][6][7][8]. Though these endoscopic resection techniques are safe to perform in individuals with IBD, the frequency of post-procedural recurrence of polyps is higher, and it is more technically difficult to use these techniques to remove a fibrotic, non-lifting adenoma [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Endoscopic Full-Thickness Resection for the Management of a Polyp in a Patient With Ulcerative Colitis

Baker¹,

Kochhar²,

Vadaketh³

2022

Cureus

View full text Add to dashboard Cite

Endoscopic full-thickness resection (EFTR) is an endoscopic technique utilized to excise challenging gastrointestinal lesions. While the safety and efficacy of EFTR are well-documented in the general population, its utilization in patients with inflammatory bowel disease (IBD) has not been reported. Here, we present a patient with a longstanding history (more than 10 years) of ulcerative colitis (UC) who was recently found to have a large, fibrotic, non-lifting adenoma in her descending colon. After a multidisciplinary discussion, it was determined that the best way to remove the adenoma would be by EFTR. To our knowledge, this is the first reported case that details the use of EFTR in a patient with IBD. The procedure was successful, and the patient did not experience any complications during the procedure or upon clinical follow-up.

show abstract

Endoscopic resection for non-polypoid dysplasia in inflammatory bowel disease: a systematic review and meta-analysis

Cited by 11 publications

References 29 publications

Minimally Invasive Endoscopic and Surgical Management of Rectal Neoplasia

Minimally Invasive Endoscopic and Surgical Management of Rectal Neoplasia

Evolving roles of magnifying endoscopy and endoscopic resection for neoplasia in inflammatory bowel diseases

Endoscopic Full-Thickness Resection for the Management of a Polyp in a Patient With Ulcerative Colitis

Contact Info

Product

Resources

About