Endoscopic resection of granular cell tumors in the gastrointestinal tract: a single center experience

Abstract

Endoscopic resection appears to be a safe and effective treatment for GCTs in the gastrointestinal tract.

A Case of Gastric Granular Cell Tumor: Review of Literature and Features of Endoscopic Ultrasonography

“…EUS were performed in the 6 cases among the recent 11 cases. 11,12,15 When we observed closely the previous cases, EUS findings of recent gastric GCTs were slightly different from those of gastric carcinoid tumors. The EUS findings of gastric GCTS were relatively inhomogenous and more echogenic, compared with gastric carcinoid tumors.…”

“…6,8 Since 2006, eleven more cases have been reported (Table 1). [9][10][11][12][13][14][15] GCTs of GI tract are usually benign, although a case of malignant gastric GCT was reported in 1996. 4 Most malignant GCTs are larger than 4 cm, and six histologic criteria were assessed: necrosis, spindling, vesicular nuclei with large nucleoli, increased mitotic activity (＞2 mi-toses/10 high power fields), high nuclear to cytoplasmic ratio, and pleomorphism.…”

“…Since 2006, eleven cases of gastric GCT have been reported. [9][10][11][12][13][14][15] Ten cases could be found in the PubMed (US National Library of Medicine) and were written in English 9,10,12-15 and a single case was written in Korean. 11 Among of eleven cases, EUS was performed in six cases.…”

“…11 Among of eleven cases, EUS was performed in six cases. 11,12,15 We report a case of a 31-year-old man with GCT of stomach, seemed like carcinoid, and we review the endoscopic findings and EUS findings of recent gastric GCT cases.…”

Endoscopic Submucosal Dissection as Diagnostic Treatment for Gastric Granular Cell Tumor Confined to the Submucosa

“…The incidence of gastric GCT is very rare [3,4]. Although most GCTs that originate from Schwann cells are benign, about 2% of malignant cases have been reported.…”