Endoscopic suturing closure of large mucosal defects after endoscopic submucosal dissection is technically feasible, fast, and eliminates the need for hospitalization (with videos)

Risk factors for bleeding after gastric endoscopic submucosal dissection: a systematic review and meta-analysis

“…Endoscopic suturing of large mucosal defects after gastric and colonic ESD were also reported in a single-arm study and no adverse events were seen. 86 This systematic review may help in the selection of patients who are more likely to benefit from these developing techniques.…”

The use of OverStitchTMfor the treatment of intestinal perforation, fistulas and leaks

“…The current device overcomes many of the limitations of prior devices. 10 It has been increasingly used to anchor stents within the GI lumen, 11 perform closure of perforations, 11 leaks, and fistulas, in addition to closure of mucosectomy after peroral endoscopic myotomy (POEM), 12,13 Natural Orifice Transluminal Endoscopic Surgery defect closures, 14 and perform primary and revision bariatric procedures. 15,16 This review will focus on endoscopic suturing with the OverStitch TM platform in the management of GI perforations, leaks and fistula.…”

“…The mean suturing time was 10.0 ± 5.8 minutes and successful closure without additional complication was achieved in all patients. 12 OverStitch TM case has also been utilized for the closure of full thickness esophagotomy defects which developed during POEM procedures.…”

Endoscopic creation of an omental patch with an over-the-scope clip system after endoscopic excavation and resection of a large gastrointestinal stromal tumor of the stomach

“…the past perforation was always considered a catastrophe, full-thickness wall defects can nowadays be completely closed with the use of endoscopic devices such as clips, Endoloops, suturing devices, and OTSC systems [2,3]. Whereas closure of a defect used to focus mainly on apposition of the perforation edges, we believe that the creation of an endoscopic omental patch may add strength and improve sealing of the perforation site.…”