Endoscopic Ultrasonography and Contrast-Enhanced Endoscopic Ultrasonography

Kitano, Masayuki; Kudo, Masatoshi; Sakamoto, Hiroki; Komaki, Takamitsu

doi:10.1159/000323493

Cited by 43 publications

(34 citation statements)

References 34 publications

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“…Furthermore, CEU is used in several other clinical conditions, for example, gestational trophoblastic diseases, arthritis, and cancer, because of greater sensitivity, as compared with ultrasound Doppler alone. 12,30,36 In this respect, one could envisage CEU as a technical enhancement of an existing tool (ultrasound) that provides an additional means of assessment to the existing lines of investigation, for example, ultrasound and ultrasound Doppler. Indeed, it may even facilitate the earlier clinical detection of tendinopathy than has hitherto been possible.…”

Section: Discussionmentioning

confidence: 99%

The Microvascular Volume of the Achilles Tendon Is Increased in Patients With Tendinopathy at Rest and After a 1-Hour Treadmill Run

et al. 2013

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Section: Discussionmentioning

confidence: 99%

The Microvascular Volume of the Achilles Tendon Is Increased in Patients With Tendinopathy at Rest and After a 1-Hour Treadmill Run

et al. 2013

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“…To this end, new techniques such as contrast-enhanced EUS and EUS elastography have emerged. Contrast-enhanced EUS has recently been reviewed elsewhere2122 and will not be covered in this article.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic ultrasound elastography

Iglesias‐García

Lindkvist

Lariño‐Noia

et al. 2012

Endosopic Ultrasound

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Endoscopic ultrasound (EUS) is a reference technique for diagnosing and staging several different diseases. EUS-guided biopsies and fine needle aspirations are used to improve diagnostic performance of cases where a definitive diagnosis cannot be obtained through conventional EUS. However, EUS-guided tissue sampling requires experience and is associated with a low but not negligible risk of complications. EUS elastography is a non-invasive method that can be used in combination with conventional EUS and has the potential for improving the diagnostic accuracy and reducing the need for EUS-guided tissue sampling in several situations. Elastography measures tissue stiffness by evaluating changes in the EUS image before and after the application of slight pressure to the target tissue by the ultrasonography probe. Pathologic processes such as cancerization and fibrosis alter tissue elasticity and therefore induce changes in elastographic appearance. Qualitative elastography depicts tissue stiffness using different colors, whereas quantitative elastography renders numerical results expressed as a strain ratio or hue histogram mean. EUS elastography has been proven to differentiate between benign and malignant solid pancreatic masses, as well as between benign and malignant lymph nodes with a high accuracy. Studies have also demonstrated that the early changes of chronic pancreatitis can be distinguished from normal pancreatic tissues under EUS elastography. In this article, we review the technical aspects and current clinical applications of qualitative and quantitative EUS elastography and emphasize the potential additional indications that need to be evaluated in future clinical studies.

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“…Occasionally, CE-EUS can differentiate small pancreatic carcinomas that cannot be detected by other imaging modalities [15,27]. In one study, seven ductal carcinomas and two neuroendocrine tumors showed hypoenhancement and hyperenhancement, respectively, on CH-EUS in 12 neoplasms that were not detected by MDCT [27].…”

Section: Discussionmentioning

confidence: 99%

“…Because EUS can acquire high-resolution images of the pancreas, it is considered a highly sensitive method for evaluating and diagnosing pancreatic lesions, when compared with other imaging modalities [15,16]. However, EUS has limitations in evaluating intratumoral vascular structures or enhancement patterns in the characterization of pancreatic lesions because it lacks enhancing technology.…”

Section: Clinical Applications: Diagnosismentioning

confidence: 99%

Contrast-enhanced endoscopic ultrasonography: advance and current status

Jang

Lee

2014

Ultrasonography

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Endoscopic ultrasonography (EUS) technology has undergone a great deal of progress along with the color and power Doppler imaging, three-dimensional imaging, electronic scanning, tissue harmonic imaging, and elastography, and one of the most important developments is the ability to acquire contrast-enhanced images. The blood flow in small vessels and the parenchymal microvasculature of the target lesion can be observed non-invasively by contrast-enhanced EUS (CE-EUS). Through a hemodynamic analysis, CE-EUS permits the diagnosis of various gastrointestinal diseases and differential diagnoses between benign and malignant tumors. Recently, mechanical innovations and the development of contrast agents have increased the use of CE-EUS in the diagnostic field, as well as for the assessment of the efficacy of therapeutic agents. The advances in and the current status of CE-EUS are discussed in this review.

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Endoscopic Ultrasonography and Contrast-Enhanced Endoscopic Ultrasonography

Cited by 43 publications

References 34 publications

The Microvascular Volume of the Achilles Tendon Is Increased in Patients With Tendinopathy at Rest and After a 1-Hour Treadmill Run

The Microvascular Volume of the Achilles Tendon Is Increased in Patients With Tendinopathy at Rest and After a 1-Hour Treadmill Run

Endoscopic ultrasound elastography

Contrast-enhanced endoscopic ultrasonography: advance and current status

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