Endoscopic Versus Microscopic Transsphenoidal Surgery in the Treatment of Pituitary Adenoma: A Systematic Review and Meta-Analysis

Outcomes of endoscopic and microscopic transsphenoidal surgery on non‐functioning pituitary adenomas: a systematic review and meta‐analysis

“…Similarly, in the meta-analysis performed by Gao et al, the rate of GTR was higher in the endoscopic group than that in the microscopic group, as well as less frequency perforation in patients underwent endoscopic surgery [4]. In consistence, Li et al concluded that endoscopic transsphenoidal surgery was associated with higher incidence of GTR [5]. A major prognostic factor for the resection outcome and recurrence of a pituitary adenoma is its parasellar extension, particularly into the space of the cavernous sinus.…”

“…In consistence, Li et al . concluded that endoscopic transsphenoidal surgery was associated with higher incidence of GTR . A major prognostic factor for the resection outcome and recurrence of a pituitary adenoma is its parasellar extension, particularly into the space of the cavernous sinus.…”

“…A major prognostic factor for the resection outcome and recurrence of a pituitary adenoma is its parasellar extension, particularly into the space of the cavernous sinus. With the panoramic visualization, endoscopy provides a wider and superior pathway to the area of parasellar and suprasellar compartments, which may gain access to improve the rate of GTR, protection of normal pituitary tissue and thus reduce postoperative complications [5].…”

Microsurgical versus endoscopic transsphenoidal resection for acromegaly: a systematic review of outcomes and complications

“…Our findings are consistent with recent analyses suggesting that remission rates achieved by TSR are generally higher for GH-secreting microadenomas, but that endoscopic TSR may achieve improved rates of complete tumor resection and biochemical remission for macroadenomas. [79–81]…”

Supracerebellar Infratentorial Endoscopic and Endoscopic-Assisted Approaches to Pineal Lesions: Technical Report and Review of the Literature

“…The current “four hands, two nostrils” technique offers the lowest rates of infection and comorbidities associated with trans-sphenoidal endoscopy, minimizes entry trauma, and affords greater area of exposure and surgical freedom [11]. A recent systematic review and meta-analysis found endoscopy to be associated with higher gross total tumor resection, lower rate of septal perforation in treating pituitary adenomas, and lower incidence rates of residual tumor in comparison to microsurgery [12]. Additionally, a recent multicenter study has demonstrated endoscopy to have equal outcomes to microscopy, in the treatment of pituitary adenomas, despite a vast difference in surgeon experience (100 independent cases versus 1800) [13].…”