Introduction: S ¸erefeddin Sabuncuog ˘lu, in his surgical medicine book entitled ''Imperial Surgery'' (Cerra ˆhiyetu ¨'l-Ha ˆniyye) that was published in the 15th century, described many diseases using colored miniatures, and explained the repair of these conditions using surgical methods and the required patient care after surgery. In his handwritten treatise, Sabuncuog ˘lu raised the curtain on his surgical methods with his illustrations. As a first in medical history, Sabuncuog ˘lu's book should be considered one of the most important original works from that era. Materials and Method: The handwritten ''Imperial Surgery'' is presented in three chapters divided into 194 sections, and describing 147 surgical procedures with miniature drawings, 160 surgical instruments and 10 types of incision. Results: A separate chapter is allocated to craniomaxillofacial surgery in Imperial Surgery, containing 53 of the total 194 sections. The first chapter describes the use of branding (cauterization) for the treatment of headache and facial diseases. The second chapter describes the treatment of hydrocephalus, headache, vascular surgery, and the surgical treatment of tumors in the head and face. The third chapter describes in detail the treatment of cranial fractures, nasal fractures, mandibular fractures and mandibular dislocations.
Conclusion:The basic craniomaxillofacial surgery concepts, the descriptions of craniomaxillofacial diseases, the scales indicating the general patient conditions, and the surgical therapies, incisions, surgical instruments, postoperative care and complications put forward in the book are discussed in the present study. In the light of this seminal study, the authors of the present study suggest that Sabuncuog ˘lu should be considered and dignified as one of the leading pioneers of craniomaxillofacial surgery.