Endospore production of Bacillus spp. for industrial use

Abstract

The increased occurrence of antibiotic resistance and the harmful use of pesticides are a major problem of modern times. A ban on the use of antibiotics as growth promoters in animal breeding has put a focus on the probiotics market. Probiotic food supplements are versatile and show promising results in animal and human nutrition. Chemical pesticides can be substituted by biopesticides, which are very effective against various pests in plants due to increased research. What these fields have in common is the use of spore‐forming bacteria. The endospore‐forming Bacillus spp. belonging to this group offer an effective solution to the aforementioned problems. Therefore, the biotechnological production of sufficient qualities of such endospores has become an innovative and financially viable field of research. In this review, the production of different Bacillus spp. endospores will be reviewed. For this purpose, the media compositions, cultivation conditions and bioprocess optimization methods of the last 20 years are presented and reflected.

Endogenous cell wall degrading enzyme LytD is important for the biocontrol activity of Bacillus subtilis

“…Bacteria from genus Bacillus are considered as one of the most important microorganisms in biological control against plant diseases of various crops ( Fira et al., 2018 ; Villarreal-Delgado et al., 2018 ; Etesami et al., 2023 ). Besides the high efficacy against phytopathogens, additional advantages of using these bacteria include the ease of culture, storage, and manufacture due to the ability of Bacillus to produce endospores ( Biermann and Beutel, 2023 ). In recent years, commercial formulated Bacillus -based biological pesticides have been increasingly used to control various plant diseases worldwide.…”