Endothelial Cell Fibrin Gel Angiogenesis Bead Assay

Clavane, Eva M; Taylor, Hannah A; Cubbon, Richard M

doi:10.1007/978-1-0716-2059-5_25

Cited by 3 publications

(3 citation statements)

References 5 publications

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“…Cell culture cytotoxicity assays were performed as described 46,47 using human lung carcinoma cells A549, 48 colorectal carcinoma cells HCT-116, 49 pancreatic adenocarcinoma cells PNS1, 50 and glioblastoma multiforme cells T98G. 51 The tube formation inhibition assay was performed as described 52 using bovine aortic endothelial cells (BAECs).…”

Section: ■ Results and Discussionmentioning

confidence: 99%

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OSMAC Approach and Cocultivation for the Induction of Secondary Metabolism of the Fungus Pleotrichocladium opacum

Rodríguez Martín-Aragón,

Trigal Martínez,

Cuadrado

et al. 2023

ACS Omega

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Section: ■ Results and Discussionmentioning

confidence: 99%

“…The tube formation inhibition assay was performed as described 52 using bovine aortic endothelial cells (BAECs). 53 …”

Section: Methodsmentioning

confidence: 99%

OSMAC Approach and Cocultivation for the Induction of Secondary Metabolism of the Fungus Pleotrichocladium opacum

Rodríguez Martín-Aragón,

Trigal Martínez,

Cuadrado

et al. 2023

ACS Omega

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“…It was successfully used to promote anastomosis in vitro by the coculturing of endothelial cells (ECs) and fibroblasts in a fibrin 3D gel [98]. In vitro, a hydrogel material can be created by mixing fibrinogen with thrombin and calcium ions [99][100][101]. Fibrin-based hydrogels, renowned for their ability to promote vasculogenesis, are commonly employed in various models of vascularization due to their ease of fabrication [99,100,[102][103][104][105].…”

Section: Naturally Derived Hydrogelsmentioning

confidence: 99%

Mimicking Molecular Pathways in the Design of Smart Hydrogels for the Design of Vascularized Engineered Tissues

Nicosia,

Salamone,

Costa

et al. 2023

IJMS

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Biomaterials are pivotal in supporting and guiding vascularization for therapeutic applications. To design effective, bioactive biomaterials, understanding the cellular and molecular processes involved in angiogenesis and vasculogenesis is crucial. Biomaterial platforms can replicate the interactions between cells, the ECM, and the signaling molecules that trigger blood vessel formation. Hydrogels, with their soft and hydrated properties resembling natural tissues, are widely utilized; particularly synthetic hydrogels, known for their bio-inertness and precise control over cell–material interactions, are utilized. Naturally derived and synthetic hydrogel bases are tailored with specific mechanical properties, controlled for biodegradation, and enhanced for cell adhesion, appropriate biochemical signaling, and architectural features that facilitate the assembly and tubulogenesis of vascular cells. This comprehensive review showcases the latest advancements in hydrogel materials and innovative design modifications aimed at effectively guiding and supporting vascularization processes. Furthermore, by leveraging this knowledge, researchers can advance biomaterial design, which will enable precise support and guidance of vascularization processes and ultimately enhance tissue functionality and therapeutic outcomes.

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Targeting RNA helicase DDX3X with a small molecule inhibitor for breast cancer bone metastasis treatment

Winnard,

Vesuna,

Bol

et al. 2024

Cancer Letters

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Endothelial Cell Fibrin Gel Angiogenesis Bead Assay

Cited by 3 publications

References 5 publications

OSMAC Approach and Cocultivation for the Induction of Secondary Metabolism of the Fungus Pleotrichocladium opacum

OSMAC Approach and Cocultivation for the Induction of Secondary Metabolism of the Fungus Pleotrichocladium opacum

Mimicking Molecular Pathways in the Design of Smart Hydrogels for the Design of Vascularized Engineered Tissues

Targeting RNA helicase DDX3X with a small molecule inhibitor for breast cancer bone metastasis treatment

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