2000
DOI: 10.1046/j.1432-0436.2000.6550287.x
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Endothelial-like cells derived from human CD14 positive monocytes

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Cited by 305 publications
(73 citation statements)
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“…on May 10, 2018. by guest www.bloodjournal.org From cells, 10,12,13,22 side population cells, 23 and circulating mature endothelial cells. 24 Thus, the circulating cell population that contributes to postnatal neovascularization is heterogenous and displays variable morphologic growth characteristics.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…on May 10, 2018. by guest www.bloodjournal.org From cells, 10,12,13,22 side population cells, 23 and circulating mature endothelial cells. 24 Thus, the circulating cell population that contributes to postnatal neovascularization is heterogenous and displays variable morphologic growth characteristics.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, within these populations, it may be that only a small, specific fraction of cells has this capacity. Earlier studies have demonstrated that circulating monocytes can develop an endothelial phenotype 10,22 and that they have the ability to take part in neovascularization. 13 A recent study demonstrated that peripheral-blood endothelial-like cells are derived from monocytes/macrophages.…”
Section: Discussionmentioning
confidence: 99%
“…Production of growth factors and metalloproteinases certainly contribute to the angiogenic potential of macrophages as demonstrated previously by Arras et al 9 Previous studies also demonstrated that certain macrophage subsets have the potential to transform into other cell types including vascular cells. 31,32 However, it remains unknown whether these phenotypical changes relate to a functional integration of these cells into growing vessels.…”
Section: Khmelewski Et Al Role Of Tissue Resident Cells In Arteriogenmentioning
confidence: 99%
“…10,11 Several recent reports have demonstrated that endothelial-like cells can be generated in vitro by plating highly purified populations of human CD14 ϩ monocytes. [12][13][14][15][16] Still, the cell type from which CE-EPCs are derived and whether CD14 ϩ cells can generate CE-EPCs that contrib-ute to functional vasculature in vivo is unclear. 17,18 Although the phenotype of CE-EPCs has been extensively characterized, 10,[13][14][15][16] its in vivo relevance is unclear.…”
mentioning
confidence: 99%