Endothelial Response to Overnight Corneal Reshaping

Abstract

Corneal endothelial polymegathism and pleomorphism can decrease with properly prescribed and monitored overnight corneal reshaping lenses over some standard contact lenses.

Two single descriptors of endothelial polymegethism and pleomorphism

“…We do not mean that previous researchers assume ECD or surface area as a single measurement of the degree of polymegethism. However, those parameters have been considered as single indicators of endothelial health, as several clinical studies in the fields of cataract surgery [12], diabetes, corneal refractive surgery [10], refractive surgery with intra-ocular lens implantation [17], contact lenses [6,18] and penetrating keratoplasty [10,19] use ECD as unique or major outcome for monitoring endothelium health changes related with the condition/intervention. Other studies combine several parameters to characterize endothelial health of the cornea within these areas of research [7,9,[20][21][22][23].…”