Endothelium-targeted NF-κB siRNA nanogel for magnetic resonance imaging and visualized-anti-inflammation treatment of atherosclerosis

Guo, Yuanyuan; Wang, Fujun; Wan, Sunli; Liu, Xinhua; Huang, Yu; Xie, Miao; Wei, Xiaoer; Zhu, Wangshu; Yao, Tingting; Li, Yuehua; Zhang, Chuan; Zhu, Yueqi

doi:10.1016/j.biomaterials.2024.122897

Biomaterials

2025

DOI: 10.1016/j.biomaterials.2024.122897

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Endothelium-targeted NF-κB siRNA nanogel for magnetic resonance imaging and visualized-anti-inflammation treatment of atherosclerosis

Yuanyuan Guo,

Fujun Wang,

Sunli Wan

et al.

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Nano Delivery System for Atherosclerosis

Rong,

He,

Fan

et al. 2024

JFB

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Atherosclerosis, a pathological process propelled by inflammatory mediators and lipids, is a principal contributor to cardiovascular disease incidents. Currently, drug therapy, the primary therapeutic strategy for atherosclerosis, faces challenges such as poor stability and significant side effects. The advent of nanomaterials has garnered considerable attention from scientific researchers. Nanoparticles, such as liposomes and polymeric nanoparticles, have been developed for drug delivery in atherosclerosis treatment. This review will focus on how nanoparticles effectively improve drug safety and efficacy, as well as the continuous development and optimization of nanoparticles of the same material and further explore current challenges and future opportunities in this field.

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Nano Delivery System for Atherosclerosis

Rong,

He,

Fan

et al. 2024

JFB

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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Endothelium-targeted NF-κB siRNA nanogel for magnetic resonance imaging and visualized-anti-inflammation treatment of atherosclerosis

Cited by 1 publication

References 44 publications

Nano Delivery System for Atherosclerosis

Nano Delivery System for Atherosclerosis

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