Endotherapy is effective for pancreatic ductal disruption: A dual center experience

Das, Rohit; Papachristou, Georgios I.; Slivka, Adam; Easler, Jeffrey J.; Chennat, Jennifer; Malin, Jessica; Herman, Justin; Laique, Sobia N.; Hayat, Umar; Ooi, Yinn Shaung; Rabinovitz, Mordechai; Yadav, Dhiraj; Siddiqui, Ali A.

doi:10.1016/j.pan.2015.12.176

Cited by 33 publications

(31 citation statements)

References 23 publications

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“…5,[17][18][19][20][21][22] Further, a multicentre study in adults 23 and a multicentre study in children 16 and several larger single, dual, or multi-centre cohorts were included. [24][25][26][27][28][29][30][31][32][33][34]…”

Section: Resultsmentioning

confidence: 99%

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Clinical update on management of pancreatic trauma

Søreide

Weiser

Parks

2018

HPB

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Section: Resultsmentioning

confidence: 99%

“…Successful endoscopic stenting as a final therapy is usually reported to be associated with a relatively low prevalence of trauma-related leaks in these series. 25…”

Section: Hpbmentioning

confidence: 99%

Clinical update on management of pancreatic trauma

Søreide

Weiser

Parks

2018

HPB

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“…Moving forward to the present, the current state of scientific evidence on the topic of endoscopic intervention for pancreatic fistula is limited to retrospective data, mostly case series. More recent, larger retrospective studies that assess endoscopic therapy for PD disruption include mostly patients who manifest with peri-pancreatic fluid collections and only a small number of patients with pancreatic fistulae [15,49,53,54]. Regarding the overlap of peri-pancreatic collection and pancreatic fistula, given the concern for suboptimal drainage and superinfection of the collection with transpapillary therapy alone, consideration should be given to endoscopic transmural drainage especially if a mature fluid collection is larger than 6 centimeters or solid debris is present [55].…”

Section: Endoscopic Treatmentmentioning

confidence: 99%

Treatment of Pancreatic Leaks and Fistulae

Miller¹,

Pleskow²

2020

Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy

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Pancreatic fistulae occur as a result of pancreatic duct disruption, most often in the context of pancreatitis, surgery, or trauma. They are categorized as external if they communicate with the skin or internal if they connect with epithelialized spaces within the body, most commonly the peritoneal or pleural cavities, resulting in ascites or pleural effusion, respectively. They are a leading cause of morbidity and mortality in patients post pancreatic surgery, and they are associated with multiple systemic complications independent of their etiology. Conservative treatment aims to decrease pancreatic exocrine secretions and includes nutritional support and somatostatin analogue therapy, yet a significant proportion of patients will not

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“…Transpapillary stent placement into the disconnected upstream segment is generally unsuccessful, but given the implications an attempt may be worthwhile if the gap is reasonable because successful bridging can occur ( Figure 6). 19,75,76 If the disconnected upstream duct is not initially opacified, placement of a transpapillary stent into the disruption occasionally results in sufficient collapse of the cavity around the stent to restore ductal continuity at the time of follow-up ERCP, but this approach is not evidence-based and some endoscopists prefer to place a stent in the downstream duct. The definitive treatment of this condition is surgery to drain or remove the disconnected segment; however, the operation can be morbid and removal of additional pancreatic parenchyma can lead to diabetes.…”

Section: Disconnected Pancreatic Ductmentioning

confidence: 99%

Endoscopic Drainage of Pancreatic Fluid Collections

Elmunzer

2018

Clinical Gastroenterology and Hepatology

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Endoscopy has emerged as a mainstay in the management of pancreatic fluid collections (PFCs), representing an important advance in clinical medicine that has significantly improved the risk-benefit ratio of treating this complex patient population. While endoscopic pseudocyst drainage has generally supplanted surgical and percutaneous approaches, the optimal strategy for walled-off necrosis remains variable and multi-disciplinary despite an emerging trend from randomized trials favoring endoscopy. Although several issues pertaining to endoscopic drainage appear to have been settled - such as the use of endoscopic ultrasound - other pressing questions - including the optimal prosthesis and debridement strategy - remain unanswered, and rigorous investigation is needed. This review aims to provide an evidence-based but practical appraisal of the endoscopic drainage of PFCs through the perspective of the author, with an emphasis on relevant clinical and endoscopic considerations and important research questions.

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Endotherapy is effective for pancreatic ductal disruption: A dual center experience

Cited by 33 publications

References 23 publications

Clinical update on management of pancreatic trauma

Clinical update on management of pancreatic trauma

Treatment of Pancreatic Leaks and Fistulae

Endoscopic Drainage of Pancreatic Fluid Collections

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