Abstract:Summary: During intensive care, the severity of gut-derived systemic endotoxaemia in 16 patients with active Crohn's disease was characterized by the simultaneous determination of elastase/ai-proteinase-inhibitor and L/ww/ws-amoebocyte-lysate-reactivity. Using both assays in 15/16 patients the detectable endotoxic activity during the disease course was reflected by a parallelism between elastase/a r proteinase-inhibitor and Limulusamoebocyte-lysate-reactivity. In 8 gut-irrigated patients, significantly lower e… Show more
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