1984
DOI: 10.1136/bmj.288.6422.965
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Endotracheal cuff pressure and tracheal mucosal blood flow: endoscopic study of effects of four large volume cuffs.

Abstract: Large volume, low pressure endotracheal tube cuffs are claimed to have less deleterious effect on tracheal mucosa than high pressure, low volume cuffs. Low pressure cuffs, however, may easily be overinflated to yield pressures that will exceed capillary perfusion pressure. Various large volume cuffed endotracheal tubes were studied, including Portex Profile, Searle Sensiv, Mallinkrodt Hi-Lo, and Lanz. Tracheal mucosal blood flow in 40 patients undergoing surgery was assessed using an endoscopic photographic te… Show more

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Cited by 535 publications
(412 citation statements)
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“…2,26 Moreover, one case in group T showed a cuff pressure of 60 cm H 2 O, an amount that is known to block the circulation of the trachea completely. 4 Tracheal mucosal blood flow can be influenced by various factors such as perfusion pressure and vasomotor status. To prevent a decrease in tracheal mucosal blood flow, intraoperative blood pressure should be cautiously monitored, because intraoperative hypotension can impair tracheal mucosal blood flow by reducing perfusion pressure.…”
Section: Discussionmentioning
confidence: 99%
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“…2,26 Moreover, one case in group T showed a cuff pressure of 60 cm H 2 O, an amount that is known to block the circulation of the trachea completely. 4 Tracheal mucosal blood flow can be influenced by various factors such as perfusion pressure and vasomotor status. To prevent a decrease in tracheal mucosal blood flow, intraoperative blood pressure should be cautiously monitored, because intraoperative hypotension can impair tracheal mucosal blood flow by reducing perfusion pressure.…”
Section: Discussionmentioning
confidence: 99%
“…[1][2][3] A cuff pressure of more than 30 cm H 2 O is known to cause obstruction to mucosal blood flow in the trachea. 4 Partial denuding of the basement membrane was found at an ETT cuff pressure over 50 cm H 2 O. 4 An increase in the ETT cuff pressure is associated with increased postoperative complications such as postoperative sore throat and hoarseness.…”
Section: Résumémentioning
confidence: 99%
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“…An infl ating cuff pressure less than 20 cmH 2 O may favor secretion drainage, while a pressure greater than 30 cmH 2 O may result in mucosal injury [18]. Despite routine cuff pressure controls, variations in ETT cuff pressure frequently occur, exposing patients to increased risk of VAP [19].…”
Section: Cuff Carementioning
confidence: 99%
“…The valve of the pilot balloon of the bronchial cuff was connected to an aneroid manometer (Mallinckrodt Medical, Athlone, Ireland) via a threeway stopcock followed by inflation of the bronchial cuff with air at a pressure of 35 cm H 2 O which is sufficient to seal the bronchus, 3 and around which bronchial mucosal damage can be minimized. [4][5][6] The volume of air injected into the cuff at this position was recorded. Two-lung ventilation was changed to right-sided, onelung ventilation with the minute volume of 0.1 L·kg -1 at a rate of 20 bpm.…”
Section: Methodsmentioning
confidence: 99%