Endovascular Management of Deep Vein Thrombosis with Rheolytic Thrombectomy: Final Report of the Prospective Multicenter PEARL (Peripheral Use of AngioJet Rheolytic Thrombectomy with a Variety of Catheter Lengths) Registry

Garcia, Mark J.; Lookstein, R.; Malhotra, Rahul; Amin, Ali Hama; Blitz, Lawrence R.; Leung, Daniel A.; Simoni, Jane M.; Soukas, Peter

doi:10.1016/j.jvir.2015.01.036

Cited by 145 publications

(116 citation statements)

References 25 publications

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“…The novel RT technique provides a strong -600 mmHg suction (Venturi-) eff ect at the catheter tip which is likely the reason for the observed primary treatment success without the need for adjunctive prolonged CDT in all but two patients. This clearly is an improvement when comparing our results to the results of the PEARL study, in which 61 % of the patients treated by the fi rst-generation RT technique required adjunctive CDT to restore venous patency [13].…”

Section: Discussionsupporting

confidence: 54%

Early clinical outcomes of a novel rheolytic directional thrombectomy technique for patients with iliofemoral deep vein thrombosis

Dopheide

Sebastian

Engelberger

et al. 2018

Vasa

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Summary:Background: Rheolytic thrombectomy (RT) for acute iliofemoral deep vein thrombosis (DVT) with fi rst-generation techniques is often incomplete and adjunctive conventional catheter-directed thrombolysis (CDT) is required in more than half of patients to achieve venous patency. Patients and methods: From the prospective Bern Venous Stent Registry, we investigated rates of primary treatment success, primary patency, and post-thrombotic syndrome (PTS) from 40 consecutive patients (mean age 51 ± 19 years, 45 % women) with acute iliofemoral DVT, treated with a novel directional RT technology and stent placement. Overall, 24 patients were treated for native-vessel iliofemoral DVT (11 with single-session RT, 13 with bailout RT after failed CDT) and 16 for iliofemoral stent thrombosis. Pulse-spray thrombolysis (r-tPA 10 mg) was performed in 29 (73 %) patients. The mean follow-up duration was 193 ± 132 days (minimum 90 days). Results: Overall, primary treatment success of RT was 95 %; only two patients required adjunctive CDT to restore patency. In 24 patients with native-vessel DVT, six-month primary patency was 92 % (95 %CI 75-99 %), and 23 patients (96 %) were free from the PTS according to the Villalta score. In 16 patients with stent thrombosis, six-month primary patency was 63 % (95 %CI 35-85 %) and 50 % were free from PTS. Except for transient macroscopic haemoglobinuria in all patients, no other side effects were recorded. Conclusions: In patients with iliofemoral DVT of native or stented vessels, RT followed by stent placement appears to be effective and safe. The novel technique enables single-session DVT treatment in the majority of patients without the need for prolonged CDT.

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Section: Discussionsupporting

confidence: 54%

Early clinical outcomes of a novel rheolytic directional thrombectomy technique for patients with iliofemoral deep vein thrombosis

Dopheide

Sebastian

Engelberger

et al. 2018

Vasa

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“…Even when patients did require CDPT after AngioJet, the tPA infusion times were significantly decreased for the AngioJet group (17 vs. 48-58 hours). There was also significant improvement in quality of life at 3, 6 and 12 months (19).…”

Section: Discussionmentioning

confidence: 79%

Catheter directed interventions for acute deep vein thrombosis

Kohi

Kohlbrenner

Kolli

et al. 2016

Cardiovasc. Diagn. Ther.

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“…When these two devices are used in combination, the dosage of thrombolytic agents can be lowered further and the duration of procedure can be shortened. 6 According to the American College of Chest Physicians guidelines, PMT provides the greatest benefits for young and functionally active patients with acute presentation (<14 days, or presence of phlegmasia cerulea dolens) of extensive proximal DVT. 1 Percutaneous mechanical thrombectomy has provided promising results in various studies, while high-level evidence to guide its implementation is still lacking.…”

Section: 經皮機械血栓切除術治療急性髂股深靜脈血栓：系統綜述mentioning

confidence: 99%

Percutaneous mechanical thrombectomy in the treatment of acute iliofemoral deep vein thrombosis: a systematic review

Pc¹,

Chan²,

Law³

et al. 2019

Hong Kong Med J

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Endovascular Management of Deep Vein Thrombosis with Rheolytic Thrombectomy: Final Report of the Prospective Multicenter PEARL (Peripheral Use of AngioJet Rheolytic Thrombectomy with a Variety of Catheter Lengths) Registry

Cited by 145 publications

References 25 publications

Early clinical outcomes of a novel rheolytic directional thrombectomy technique for patients with iliofemoral deep vein thrombosis

Early clinical outcomes of a novel rheolytic directional thrombectomy technique for patients with iliofemoral deep vein thrombosis

Catheter directed interventions for acute deep vein thrombosis

Percutaneous mechanical thrombectomy in the treatment of acute iliofemoral deep vein thrombosis: a systematic review

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