Endovascular repair for abdominal aortic aneurysm followed by type B dissection

Abstract

An 86-year-old man with an abdominal aortic aneurysm was diagnosed with type B aortic dissection accompanied by a patent false lumen that started at the distal arch of the thoracic aorta and terminated at the left common iliac artery. Meticulous preoperative assessment detected 3 large intimal tears in the descending aorta, abdominal aortic aneurysm, and left common iliac artery. We performed single-stage thoracic and abdominal endovascular aneurysm repair and concomitant axillary-axillary bypass. The abdominal aortic aneurysm with type B aortic dissection was successfully treated using a single-stage endovascular stent graft, without any complications due to the careful preoperative examinations.

Study of the functional mechanisms of osteopontin and chemokine-like factor 1 in the development and progression of abdominal aortic aneurysms in rats

“…A variety of AAA risk factors can all lead to damage of the aortic wall, activation of inflammatory response, local inflammatory cell infiltration, degradation of extracellular matrix and massive induction of apoptosis in vascular smooth muscle cells, resulting in severe damage to the wall of the blood vessel, significant reduction of the main artery elasticity and ability to withstand pressure, and eventually the gradual swelling of the aortic wall due to failure to withstand the pressure of blood flow (1–3). Osteopontin (Opn) is a secreted glycosylated phosphoprotein, having important function in the extracellular matrix.…”