Endovascular Repair of Inflammatory Abdominal Aortic Aneurysms

Hinchliffe, Robert J.; Macierewicz, Jan; Hopkinson, Brian R.

doi:10.1177/152660280200900304

Cited by 37 publications

(27 citation statements)

References 19 publications

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“…In contrast, Hinchliffe et al [3] reported a regression of periaortic fibrosis in three of six patients (50%) and an unchanged situation in the remaining three. We observed even better results, with a regression of the inflammatory tissue and the periaortic fibrosis in all five patients and a complete disappearance in three of them These facts enforce endovascular aneurysm repair as an attractive alternative with better results in the regression of periaortic fibrosis.…”

Section: Discussionmentioning

confidence: 84%

“…Although atherosclerosis plays the main role in the pathogenesis, inflammatory aortic aneurysms present a minor subgroup, with an incidence ranging from 2.2-18.1% of the total number of abdominal aortic aneurysms [2]. Although the standard treatment of all aortic aneurysms still remains open surgical repair, endovascular aneurysm repair has shown promising early and midterm results [3][4][5].…”

Section: Objectivementioning

confidence: 99%

“…The perioperative mortality associated with open surgical repair of inflammatory aortic aneurysms is three times higher than that with noninflammatory aortic aneurysms, largely due to the intraoperative technical difficulties related to inflammation, such as periaortic fibrosis [6][7][8][9]. Some studies and case reports have proposed that endovascular aneurysm repair can reduce this increased risk of complications with equally good results in aneurysm exclusion and aneurysm rupture prevention [3].…”

Section: Objectivementioning

confidence: 99%

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Endovascular Repair of Inflammatory Aortic Aneurysms: Long-Term Results

Puchner¹,

Bucek²,

Loewe³

et al. 2006

American Journal of Roentgenology

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Section: Discussionmentioning

confidence: 84%

Section: Objectivementioning

confidence: 99%

Section: Objectivementioning

confidence: 99%

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Endovascular Repair of Inflammatory Aortic Aneurysms: Long-Term Results

Puchner¹,

Bucek²,

Loewe³

et al. 2006

American Journal of Roentgenology

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“…Resolution of periaortic fibrotic tissue after surgery for IAAA is still debated. Some investigators have reported complete resolution whilst others have noted partial regression and even persistence of the inflammatory cuff [74][75][76]. New low-grade periaortic fibrosis has been reported after endovascular repair in a small number of patients [76].…”

Section: Treatmentmentioning

confidence: 99%

Chronic periaortitis

Jois

2004

Rheumatology

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Chronic periaortitis commonly involves the infrarenal portion of the abdominal aorta. Idiopathic retroperitoneal fibrosis, inflammatory abdominal aortic aneurysm and perianeurysmal retroperitoneal fibrosis are its various clinical presentations. They present as a non-specific systemic inflammatory disorder and may lead to ureteric obstruction and consequent renal failure. An exaggerated inflammatory response to advanced atherosclerosis has been thought to be the main pathogenetic process. Autoimmunity has also been proposed as a contributing factor. Contrast-enhanced CT scanning is the diagnostic test of choice. Steroids and immunosuppressive agents are successfully used in the treatment of idiopathic retroperitoneal fibrosis and selected cases of inflammatory abdominal aortic aneurysm, and surgery is used in others. Early diagnosis is important in order to reduce morbidity from complications such as renal failure and mortality from aortic rupture.

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“…The material that has become favoured over the years is woven polyester (Dacron). steel is currently used for both self-expanding and balloon expandable varieties of stents, whereas Polyester and expanded polytetrafluoroethylene (ePTFE) form the basis of current stent-graft nitinol is only currently used for the self-expanding varieties [26].…”

Section: Delivery Systemsmentioning

confidence: 99%

Development of endovascular stent-grafts

Hinchliffe

Hopkinson

2007

Proc Inst Mech Eng H

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The very first experiences in the early 1990s with endovascular aortic stent-grafts were associated with significant numbers of complications including an inability to deploy the stent-graft, conversion to open surgery, and aneurysm rupture. By the mid-1990s, improved home-made and commercially available stent-grafts started to appear. These devices could be successfully deployed in the aorta, achieving aneurysm exclusion with low morbidity and mortality. However, follow-up results raised concerns about the longer-term durability. Gradually, too, these problems have been addressed such that, in the recent UK multi-centre randomized controlled trial of endovascular versus open aneurysm repair, aneurysm-related mortality was 3 per cent less in the endovascular group four years following surgery. Currently the indications for aortic stent-grafts are being expanded. It is now possible to maintain perfusion successfully in aortic side branches and to treat aneurysms that would have once been thought untreatable. This review paper reviews the main developments in endovascular stent-grafting and the major role played by medical engineering and technology.

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Endovascular Repair of Inflammatory Abdominal Aortic Aneurysms

Cited by 37 publications

References 19 publications

Endovascular Repair of Inflammatory Aortic Aneurysms: Long-Term Results

Endovascular Repair of Inflammatory Aortic Aneurysms: Long-Term Results

Chronic periaortitis

Development of endovascular stent-grafts

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