“…Medical therapy with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors ("statins") and angiotensinconverting enzyme inhibitors have been used in an effort to stabilize the plaque. 33 Systemic anticoagulation with warfarin poses a theoretic risk of inducing intraplaque hemorrhage and exacerbating the Aidinian et al, 11 2007 1 1 (100) 0 (0) 0 (0) Khoynezhad et al, 12 2007 14 0 (0) 0 (0) Brinster et al, 13 2006 21 21 (100) 0 (0) 0 (0) 0 (0) 0 (0) Caronno et al, 14 2006 4 4 (100) 0 (0) 0 (0) 0 (0) Jin et al, 15 2006 14 14 (100) 1 ( 8) 2 (17) Khamaisi et al, 16 2006 1 1 (100) 0 (0) (0) Eggebrecht et al, 17 2006 22 21 ( 95) 0 (0) 1 ( 5) 0 (0) 1 (5) Melissano et al, 18 2005 2 2 (100) 0 (0) 0 (0) Eichhofer et al, 19 2004 1 1 (100) (0) Demers et al, 20 2004 26 24 (92) 3 ( 12) 2 ( 8) 0 (0) 1 (4) Heidenreich et al, 21 2003 1 1 (100) 0 (0) 0 (0) 1 (100) D'Ancona et al, 22 2003 1 1 (100) 0 (0) Schoder et al, 23 2002 8 8 (100) 0 (0) 0 (0) 1 ( 13) Kos et al, 24 2002 10 10 (100) 1 ( 10) 5 ( 50) 1 ( 10) 0 (0) Faries et al, 25 2002 1 1 (100) 0 (0) 0 (0) 0 (0) 0 (0) Brittenden et al, 26 1999 2 2 (100) Murgo et al, 27 1998 4 4 (100) 0 (0) 1 ( 25) 1 ( 25) 0 (0) atheroemboli syndrome. 34 Despite this theoretic risk, several other studies have demonstrated reduced rates of embolization with systemic anticaoagulation.…”