Endovascular treatment for thromboangiitis obliterans (Buerger’s disease)

Carneiro, Francisco Cialdine Frota; Almeida, Bianca; Cacione, Daniel G

doi:10.1002/14651858.cd014886

Cited by 4 publications

(1 citation statement)

References 63 publications

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“…For its part, open surgery is considered a standard strategy to generate revascularization in patients with TAO and advanced limb ischemia; however, its biggest problem is bypass occlusion. 34 Because TAO involves different pathophysiological mechanisms than atherosclerosis, endovascular therapy has been proposed as one of the best alternatives through angioplasty with advantages in terms of high safety, no in-hospital mortality reported, low rate of perioperative complications and late results such as vascular permeability which favored a lower rate of limb amputations. 35 Sympathectomy is indicated in patients who have symptomatic ulcers in the fingers of the extremities and revascularization is not possible.…”

Section: Treatmentmentioning

confidence: 99%

Thromboangiitis obliterans: a review

Correa-Posada,

García-Velez,

Hurtado-Mosquera

et al. 2024

Int Surg J

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Buerger's disease was initially described by von Winiwarter in 1879 where he described it as thromboangiitis obliterans (TAO), detailing the case of spontaneous gangrene secondary to intimal proliferation. In 1908, Leo Buerger published a complete pathological description based on the amputation of a group of people who later suffered short-term gangrene. Buerger's disease or TAO is defined as a non-atherosclerotic inflammatory vasculitis that affects the small and medium vessels (including arteries and veins) of the lower and upper extremities. Although there are hypotheses about its etiopathogenesis such as the association with exposure to tobacco, few biomedical investigations have been carried out, so its direct causality remains unknown. Diagnosis continues to be a challenge, since the findings tend to be non-specific or inconsistent with suspicion, which is why it is currently based on ruling out other causes such as atherosclerosis and vasculopathies. With current evidence, there are many types of treatments, both pharmacological and non-pharmacological, with the cessation of tobacco consumption having greater evidence of results. It is essential to strengthen basic research as well as clinical trials to standardize management in this type of patient, since it is a disease with a high impact on quality of life.

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Section: Treatmentmentioning

confidence: 99%