Objectives: we present an atypical case of chronic mesenteric ischaemia with weight loss as the only clinical manifestation and endoscopic findings imitating Crohn´s disease. Materials and methods: CT angiography of the abdomen confirmed the diagnosis of mesenteric ischaemia after total occlusion of the coeliac trunk and superior mesenteric artery. Results: The patient died due to severe sepsis as a result of extended bowel infarction. Conclusions: The diagnosis of chronic mesenteric ischaemia requires a high degree of clinical suspicion and can be life-saving if made quickly.