Endovenous ablation and surgery in great saphenous vein reflux: a systematic review and network meta-analysis of randomised controlled trials protocol

Siribumrungwong, Boonying; Srikuea, Kanoklada; Orrapin, Saritphat; Benyakorn, Thoetphum; Thakkinstian, Ammarin

doi:10.1136/bmjopen-2018-024813

Cited by 10 publications

(4 citation statements)

References 35 publications

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“…The study was conducted according to the PRISMA guidelines 15 and extension statement for network meta-analysis of healthcare interventions 16 . The published protocol was registered at PROSPERO (number CRD42018096794) 17 .…”

Section: Methodsmentioning

confidence: 99%

“…MEDLINE and Scopus were searched from 2011 to March 2020. Search terms were based on patients and interventions 17 . Two reviewers independently selected studies according to predefined inclusion criteria: RCTs of GSV reflux; comparison of defined interventions as outlined below; and reporting any of the primary or secondary outcomes of interest.…”

Section: Methodsmentioning

confidence: 99%

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Interventions for great saphenous vein reflux: network meta-analysis of randomized clinical trials

Siribumrungwong

Wilasrusmee

Orrapin

et al. 2021

British Journal of Surgery

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Background A variety of endovascular and open surgical interventions exist to treat great saphenous vein reflux. However, comparisons of treatment outcomes have been inconsistent. Methods A systematic review and network meta-analysis of RCTs was performed to compare rates of incomplete stripping or non-occlusion of the great saphenous vein with or without reflux (anatomical failure) at early, mid- and long-term follow-up; and secondary outcomes (reintervention and clinical recurrence) among intervention groups. The surface under the cumulative ranking curve (SUCRA) method was used to estimate the probability of the intervention with the lowest anatomical failure rates. Results Some 72 RCTs were included. Comparisons of endothermal techniques with open surgery were mostly not significantly different, except for endovenous laser ablation (EVLA), which had higher long-term anatomical failure rates (pooled risk ratio (RR) 1.87, 95 per cent c.i. 1.14 to 3.07). Mechanochemical ablation had higher anatomical failure rates than radiofrequency ablation (RFA) (pooled RR 2.77, 1.38 to 5.53), and cyanoacrylate closure (CAC) had a RR 0.56 (0.34 to 0.93) times lower than either RFA or EVLA at the early term. Ultrasound-guided foam sclerotherapy had a higher risk of anatomical failure and reintervention than open surgery, with the lowest SUCRA value, and CAC was ranked first, third and first for best intervention for anatomical failure at early, mid and long term respectively. However, clinical recurrence rates were not significantly different between all comparisons. Conclusion Mechanochemical ablation and ultrasound-guided foam sclerotherapy performed poorly, with higher anatomical failure rates in the long term. The other treatment modalities had similar rates of anatomical failure in the short and mid term.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Interventions for great saphenous vein reflux: network meta-analysis of randomized clinical trials

Siribumrungwong

Wilasrusmee

Orrapin

et al. 2021

British Journal of Surgery

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“…The great saphenous vein (GSV) is the most common site of venous reflux, and the standard treatment is ablation of this vein. Important outcomes after GSV ablation are anatomical occlusion, abolishment of reflux in the treated vein, good function, and good quality of life for treated patients (5) . Treatment of varicose veins and spider veins is not just for cosmetic reasons.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Cosmetic Effect of Radio Frequency Ablation of Primary Varicose Veins

Abd Elwahab,

A. Abd El-Mabood,

Abd Elsamai

et al. 2024

Benha Medical Journal

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Background: Varicose veins are a common vascular disorder, often causing cosmetic concerns and decreased quality of life. Radiofrequency ablation has emerged as an effective intervention for primary varicose veins, addressing both medical and cosmetic aspects. This study aimed to evaluate the cosmetic effect of radio frequency ablation of primary varicose veins including quality of life (QoL). Patients and methods: This prospective interventional study was conducted on 40 patients diagnosed with primary varicose veins. Radiofrequency ablation was performed, and patients were assessed using various parameters, including CEAP classification, visual analogue pain scale, and quality of life measures. Results: The study included individuals with a mean age of 33.13 ± 5.5, comprising 35% males and 65% females. Intraoperative and post-procedure Pain scores (VAS) exhibited highly significant differences. The mean hospital stay was 14.00 ± 7.00 hours, the return to normal activity took 4.27 ± 1.31 days, and the return to work required 7.10 ± 1.83 days. Significant differences were observed between Preoperative and Post procedure in terms of the QoL parameter. Strong significant correlations between QoL parameter and age, CEAP, VDS, and VAS were evident in univariate and multivariate correlation regression analyses. Conclusions: Radiofrequency technologies are, effective and safe treatments for truncal venous reflux with less side effects. Radio Frequency Ablation treatments have typically short post-procedural recovery times facilitating early return to work and normal activity.

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“…Актуальність сучасної проблеми лікування ХВН та покращення якості життя пацієнтів було висвітлено в роботах Youn [1], Siribumrungwong [2], Whing [3], Farah [4], Orhurhu [5], Branisteanu [6], Azar [7], Lurie [8], Lee [9], Artemov [10], Cong [11], El Kilic [12], Giannopoulos [13], Lin [14].…”

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Оцінка Якості Життя Пацієнта На Фоні Больового Синдрому За Умов Хірургічного Лікування Хронічної Венозної Недостатності

Боднар,

Беденюк,

Боднар

et al. 2024

Перспективи та інновації науки

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Relevance of the study. Pain syndrome in chronic venous insufficiency is a common complication that correlates with the clinical degree of the disease. Although lifestyle changes remain the mainstay of treatment for pain associated with chronic venous insufficiency, compression therapy, and various pharmacological agents have become safe and effective methods of preventing this pathology. Minimally invasive surgical methods have been developed for patients for whom these measures are not sufficient. The paper describes the development of pain and analyses its intensity in patients with chronic venous insufficiency, and also considers both traditional methods of surgical treatment of pain and new advances in medical and surgical therapy of this disease.The aim: to analyse the intensity of pain in patients after endovenous laser coagulation of the great saphenous vein in the setting of chronic venous insufficiency.Materials and methods. We examined 86 patients with varicose veins of the lower extremities who were treated at the Department of Surgery of Ternopil Regional Hospital No. 2 in the period from 2021 to 2023. All patients underwent surgical treatment for varicose veins of the lower extremities: Group I -46 patients who underwent thermal obliterating methods; Group II -40 patients who underwent planned surgical intervention in the amount of combined phlebectomy with removal of the trunk of the IVC to the lower reflux limit under general anesthesia or spinal anesthesia and perforation.

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Endovenous ablation and surgery in great saphenous vein reflux: a systematic review and network meta-analysis of randomised controlled trials protocol

Cited by 10 publications

References 35 publications

Interventions for great saphenous vein reflux: network meta-analysis of randomized clinical trials

Interventions for great saphenous vein reflux: network meta-analysis of randomized clinical trials

Evaluation of Cosmetic Effect of Radio Frequency Ablation of Primary Varicose Veins

Оцінка Якості Життя Пацієнта На Фоні Больового Синдрому За Умов Хірургічного Лікування Хронічної Венозної Недостатності

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