The scramjet for cooling and heat recovery has been an issue in hypersonic vehicle. A Closed Brayton Cycle (CBC) for power generation system from the heat of cooling scramjet is proposed. Energy, in conjunction with exergy, analysis of the scramjet cooling heat driven Closed Brayton Cycle (CBC) is performed. It is observed from the analysis that, the energy and exergy efficiencies of the system are 33.90% and 24.95%, respectively. Furthermore, the exergy destruction, the output power and the conversion efficiency of CBC following the high-temperature (high-temp) heat exchanger outlet working fluid temperature and the cycle pressure ratio have been analyzed. The cycle pressure ratio, the high-temp heat exchanger outlet working fluid temperature and the low-temperature (low-temp) heat exchanger outlet fuel temperature have large effects on both energy and exergy efficiencies.